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Novel cytomegalovirus-inhibitory compounds of the class pyrrolopyridines show a complex pattern of target binding that suggests an unusual mechanism of antiviral activity.
Hahn F, Hutterer C, Henry C, Hamilton ST, Strojan H, Kraut A, Schulte U, Schütz M, Kohrt S, Wangen C, Pfizer J, Couté Y, Rawlinson WD, Strobl S, Marschall M. Hahn F, et al. Among authors: wangen c. Antiviral Res. 2018 Nov;159:84-94. doi: 10.1016/j.antiviral.2018.09.012. Epub 2018 Sep 27. Antiviral Res. 2018. PMID: 30268914
In vivo proof-of-concept for two experimental antiviral drugs, both directed to cellular targets, using a murine cytomegalovirus model.
Sonntag E, Hahn F, Bertzbach LD, Seyler L, Wangen C, Müller R, Tannig P, Grau B, Baumann M, Zent E, Zischinsky G, Eickhoff J, Kaufer BB, Bäuerle T, Tsogoeva SB, Marschall M. Sonntag E, et al. Among authors: wangen c. Antiviral Res. 2019 Jan;161:63-69. doi: 10.1016/j.antiviral.2018.11.008. Epub 2018 Nov 17. Antiviral Res. 2019. PMID: 30452929
Chemically sulfated polysaccharides from natural sources: Assessment of extraction-sulfation efficiencies, structural features and antiviral activities.
Mukherjee S, Ghosh K, Hahn F, Wangen C, Strojan H, Müller R, Anand N, Ali I, Bera K, Ray B, Hutterer C, Marschall M, Ray S. Mukherjee S, et al. Among authors: wangen c. Int J Biol Macromol. 2019 Sep 1;136:521-530. doi: 10.1016/j.ijbiomac.2019.05.005. Epub 2019 May 31. Int J Biol Macromol. 2019. PMID: 31158418
Differential upregulation of host cell protein kinases by the replication of α-, β- and γ-herpesviruses provides a signature of virus-specific signalling.
Marschall M, Strojan H, Kiener R, Wangen C, Sonntag E, Müller R, Zeitträger I, Wagner S, Stamminger T, Milbradt J, Behrends U, Körber N, Bauer T, Schrödel S, Thirion C, Wagner R, Hutterer C. Marschall M, et al. Among authors: wangen c. J Gen Virol. 2020 Mar;101(3):284-289. doi: 10.1099/jgv.0.001370. J Gen Virol. 2020. PMID: 31958050
29 results