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Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo.
Zhou GB, Kang H, Wang L, Gao L, Liu P, Xie J, Zhang FX, Weng XQ, Shen ZX, Chen J, Gu LJ, Yan M, Zhang DE, Chen SJ, Wang ZY, Chen Z. Zhou GB, et al. Among authors: wang l, wang zy. Blood. 2007 Apr 15;109(8):3441-50. doi: 10.1182/blood-2006-06-032250. Epub 2006 Dec 29. Blood. 2007. PMID: 17197433 Free PMC article.
The 12-year follow-up of survival, chronic adverse effects, and retention of arsenic in patients with acute promyelocytic leukemia.
Zhu H, Hu J, Chen L, Zhou W, Li X, Wang L, Zhao X, Zhang Y, Zhao H, Wang A, Chen Y, Sun H, Chen Q, Chen Y, Zhao W, Mi J, Shen Z, Wang Z, Chen Z, Chen S, Li J. Zhu H, et al. Blood. 2016 Sep 15;128(11):1525-8. doi: 10.1182/blood-2016-02-699439. Epub 2016 Jul 11. Blood. 2016. PMID: 27402972 Free article. No abstract available.
Expanding the use of arsenic trioxide: leukemias and beyond.
Chen Z, Chen GQ, Shen ZX, Sun GL, Tong JH, Wang ZY, Chen SJ. Chen Z, et al. Among authors: wang zy. Semin Hematol. 2002 Apr;39(2 Suppl 1):22-6. doi: 10.1053/shem.2002.33611. Semin Hematol. 2002. PMID: 12012319 Review.
3,805 results