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Beauvericin suppresses the proliferation and pulmonary metastasis of osteosarcoma by selectively inhibiting TGFBR2 pathway.
Ye G, Jiao Y, Deng L, Cheng M, Wang S, Zhang J, Ouyang J, Li Y, He Y, Tu Z, Wang Z, Song X, Wang C, Qi Q, Zhang D, Wang L, Huang M, Ye W, Chen M. Ye G, et al. Among authors: wang l, wang z, wang s, wang c. Int J Biol Sci. 2023 Aug 21;19(14):4376-4392. doi: 10.7150/ijbs.86214. eCollection 2023. Int J Biol Sci. 2023. PMID: 37781043 Free PMC article.
Discovery of Hexahydrofuro[3,2-b]furans as New Kinase-Selective and Orally Bioavailable JAK3 Inhibitors for the Treatment of Leukemia Harboring a JAK3 Activating Mutant.
Li S, Si H, Song X, Lei C, He X, Wang J, Liu Y, Zhou Y, Song JG, Peng L, Tang X, Chan S, Ren X, Tu Z, Li Z, Wang Z, Zhang Z, Ding K. Li S, et al. Among authors: wang j, wang z. J Med Chem. 2022 Aug 11;65(15):10674-10690. doi: 10.1021/acs.jmedchem.2c00922. Epub 2022 Jul 20. J Med Chem. 2022. PMID: 35860875
High-resolution neuraminidase inhibition profiling of Arnebia euchroma (Royle) I.M. Johnst. based on HR-MS and target isolation: An example study of anti-infectious constituents in traditional Chinese medicine.
Huang Y, Guo X, Wang Z, Yin C, Chen M, Xie J, Li N, Tu Z, Li J, Cao J, Jiang Z, Huang W, Tian H. Huang Y, et al. Among authors: wang z. J Ethnopharmacol. 2024 Jan 30;319(Pt 1):117074. doi: 10.1016/j.jep.2023.117074. Epub 2023 Aug 22. J Ethnopharmacol. 2024. PMID: 37619859
Discovery of a First-in-Class Degrader for the Lipid Kinase PIKfyve.
Li C, Qiao Y, Jiang X, Liu L, Zheng Y, Qiu Y, Cheng C, Zhou F, Zhou Y, Huang W, Ren X, Wang Y, Wang Z, Chinnaiyan AM, Ding K. Li C, et al. Among authors: wang z, wang y. J Med Chem. 2023 Sep 14;66(17):12432-12445. doi: 10.1021/acs.jmedchem.3c00912. Epub 2023 Aug 21. J Med Chem. 2023. PMID: 37605297 Free PMC article.
A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB.
Lin Y, Shi Q, Yang G, Shi F, Zhou Y, Wang T, Xu P, Li P, Liu Z, Sun H, Zhao Z, Ding K, Wang Z, Feng H, Yu B, Fang P, Wang J. Lin Y, et al. Among authors: wang z, wang j, wang t. Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2213670120. doi: 10.1073/pnas.2213670120. Epub 2023 Feb 7. Proc Natl Acad Sci U S A. 2023. PMID: 36749723 Free PMC article.
Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma.
Ambrogio C, Gómez-López G, Falcone M, Vidal A, Nadal E, Crosetto N, Blasco RB, Fernández-Marcos PJ, Sánchez-Céspedes M, Ren X, Wang Z, Ding K, Hidalgo M, Serrano M, Villanueva A, Santamaría D, Barbacid M. Ambrogio C, et al. Among authors: wang z. Nat Med. 2016 Mar;22(3):270-7. doi: 10.1038/nm.4041. Epub 2016 Feb 8. Nat Med. 2016. PMID: 26855149
126,474 results
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