Wang Z - Search Results

1

Chemical profiling of HIV-1 capsid-targeting antiviral PF74.

Wang L, Casey MC, Vernekar SKV, Do HT, Sahani RL, Kirby KA, Du H, Hachiya A, Zhang H, Tedbury PR, Xie J, Sarafianos SG, Wang Z. Wang L, et al. Among authors: wang z. Eur J Med Chem. 2020 Aug 15;200:112427. doi: 10.1016/j.ejmech.2020.112427. Epub 2020 May 12. Eur J Med Chem. 2020. PMID: 32438252 Free PMC article.

2

Synthesis of pyrimidine and quinolone conjugates as a scaffold for dual inhibitors of HIV reverse transcriptase and integrase.

Wang Z, Vince R. Wang Z, et al. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1293-6. doi: 10.1016/j.bmcl.2008.01.025. Epub 2008 Jan 11. Bioorg Med Chem Lett. 2008. PMID: 18226894

3

Design and synthesis of dual inhibitors of HIV reverse transcriptase and integrase: introducing a diketoacid functionality into delavirdine.

Wang Z, Vince R. Wang Z, et al. Bioorg Med Chem. 2008 Apr 1;16(7):3587-95. doi: 10.1016/j.bmc.2008.02.007. Epub 2008 Feb 8. Bioorg Med Chem. 2008. PMID: 18314335

4

Scaffold rearrangement of dihydroxypyrimidine inhibitors of HIV integrase: Docking model revisited.

Tang J, Maddali K, Pommier Y, Sham YY, Wang Z. Tang J, et al. Among authors: wang z. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3275-9. doi: 10.1016/j.bmcl.2010.04.048. Epub 2010 Apr 21. Bioorg Med Chem Lett. 2010. PMID: 20457521 Free PMC article.

5

Pharmacophore and structure-activity relationships of integrase inhibition within a dual inhibitor scaffold of HIV reverse transcriptase and integrase.

Wang Z, Tang J, Salomon CE, Dreis CD, Vince R. Wang Z, et al. Bioorg Med Chem. 2010 Jun 15;18(12):4202-11. doi: 10.1016/j.bmc.2010.05.004. Epub 2010 May 7. Bioorg Med Chem. 2010. PMID: 20576573

6

3-Hydroxypyrimidine-2,4-diones as an inhibitor scaffold of HIV integrase.

Tang J, Maddali K, Metifiot M, Sham YY, Vince R, Pommier Y, Wang Z. Tang J, et al. Among authors: wang z. J Med Chem. 2011 Apr 14;54(7):2282-92. doi: 10.1021/jm1014378. Epub 2011 Mar 7. J Med Chem. 2011. PMID: 21381765 Free PMC article.

7

The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus.

Chen YL, Tang J, Kesler MJ, Sham YY, Vince R, Geraghty RJ, Wang Z. Chen YL, et al. Among authors: wang z. Bioorg Med Chem. 2012 Jan 1;20(1):467-79. doi: 10.1016/j.bmc.2011.10.058. Epub 2011 Oct 24. Bioorg Med Chem. 2012. PMID: 22100256

8

Structural and inhibition studies of the RNase H function of xenotropic murine leukemia virus-related virus reverse transcriptase.

Kirby KA, Marchand B, Ong YT, Ndongwe TP, Hachiya A, Michailidis E, Leslie MD, Sietsema DV, Fetterly TL, Dorst CA, Singh K, Wang Z, Parniak MA, Sarafianos SG. Kirby KA, et al. Among authors: wang z. Antimicrob Agents Chemother. 2012 Apr;56(4):2048-61. doi: 10.1128/AAC.06000-11. Epub 2012 Jan 17. Antimicrob Agents Chemother. 2012. PMID: 22252812 Free PMC article.

9

C-6 aryl substituted 4-quinolone-3-carboxylic acids as inhibitors of hepatitis C virus.

Chen YL, Zacharias J, Vince R, Geraghty RJ, Wang Z. Chen YL, et al. Among authors: wang z. Bioorg Med Chem. 2012 Aug 1;20(15):4790-800. doi: 10.1016/j.bmc.2012.05.066. Epub 2012 Jun 7. Bioorg Med Chem. 2012. PMID: 22748708

10

5-Arylidenethioxothiazolidinones as inhibitors of tyrosyl-DNA phosphodiesterase I.

Sirivolu VR, Vernekar SK, Marchand C, Naumova A, Chergui A, Renaud A, Stephen AG, Chen F, Sham YY, Pommier Y, Wang Z. Sirivolu VR, et al. Among authors: wang z. J Med Chem. 2012 Oct 25;55(20):8671-84. doi: 10.1021/jm3008773. Epub 2012 Oct 8. J Med Chem. 2012. PMID: 23006064 Free PMC article.

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