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Inhibiting Type I Arginine Methyltransferase Activity Promotes T Cell-Mediated Antitumor Immune Responses.
Fedoriw A, Shi L, O'Brien S, Smitheman KN, Wang Y, Hou J, Sherk C, Rajapurkar S, Laraio J, Williams LJ, Xu C, Han G, Feng Q, Bedford MT, Wang L, Barbash O, Kruger RG, Hwu P, Mohammad HP, Peng W. Fedoriw A, et al. Among authors: wang l, wang y. Cancer Immunol Res. 2022 Apr 1;10(4):420-436. doi: 10.1158/2326-6066.CIR-21-0614. Cancer Immunol Res. 2022. PMID: 35181787 Free PMC article.
The Emerging Function and Mechanism of ceRNAs in Cancer.
Wang Y, Hou J, He D, Sun M, Zhang P, Yu Y, Chen Y. Wang Y, et al. Trends Genet. 2016 Apr;32(4):211-224. doi: 10.1016/j.tig.2016.02.001. Epub 2016 Feb 24. Trends Genet. 2016. PMID: 26922301 Free PMC article. Review.
18F-fluorodeoxyglucose positron emission tomography correlates with tumor immunometabolic phenotypes in resected lung cancer.
Mitchell KG, Amini B, Wang Y, Carter BW, Godoy MCB, Parra ER, Behrens C, Villalobos P, Reuben A, Lee JJ, Weissferdt A, Moran CA, Fujimoto J, Sepesi B, Walsh GL, Vaporciyan AA, Hofstetter WL, William WN Jr, Gibbons DL, Wang J, Hwu P, Swisher SG, Piwnica-Worms D, Kadara H, Wistuba II, Heymach JV, Peng W, Cascone T. Mitchell KG, et al. Among authors: wang j, wang y. Cancer Immunol Immunother. 2020 Aug;69(8):1519-1534. doi: 10.1007/s00262-020-02560-5. Epub 2020 Apr 16. Cancer Immunol Immunother. 2020. PMID: 32300858 Free PMC article.
Integrating genome-wide CRISPR immune screen with multi-omic clinical data reveals distinct classes of tumor intrinsic immune regulators.
Hou J, Wang Y, Shi L, Chen Y, Xu C, Saeedi A, Pan K, Bohat R, Egan NA, McKenzie JA, Mbofung RM, Williams LJ, Yang Z, Sun M, Liang X, Rodon Ahnert J, Varadarajan N, Yee C, Chen Y, Hwu P, Peng W. Hou J, et al. Among authors: wang y. J Immunother Cancer. 2021 Feb;9(2):e001819. doi: 10.1136/jitc-2020-001819. J Immunother Cancer. 2021. PMID: 33589527 Free PMC article.
Systematic functional interrogation of human pseudogenes using CRISPRi.
Sun M, Wang Y, Zheng C, Wei Y, Hou J, Zhang P, He W, Lv X, Ding Y, Liang H, Hon CC, Chen X, Xu H, Chen Y. Sun M, et al. Among authors: wang y. Genome Biol. 2021 Aug 23;22(1):240. doi: 10.1186/s13059-021-02464-2. Genome Biol. 2021. PMID: 34425866 Free PMC article.
LFA-1 activation enriches tumor-specific T cells in a cold tumor model and synergizes with CTLA-4 blockade.
Hickman A, Koetsier J, Kurtanich T, Nielsen MC, Winn G, Wang Y, Bentebibel SE, Shi L, Punt S, Williams L, Haymaker C, Chesson CB, Fa'ak F, Dominguez AL, Jones R, Kuiatse I, Caivano AR, Khounlo S, Warier ND, Marathi U, Market RV, Biediger RJ, Craft JW Jr, Hwu P, Davies MA, Woodside DG, Vanderslice P, Diab A, Overwijk WW, Hailemichael Y. Hickman A, et al. Among authors: wang y. J Clin Invest. 2022 Jul 1;132(13):e154152. doi: 10.1172/JCI154152. J Clin Invest. 2022. PMID: 35552271 Free PMC article.
CRISPR-mediated TGFBR2 knockout renders human ovarian cancer tumor-infiltrating lymphocytes resistant to TGF-β signaling.
Fix SM, Forget MA, Sakellariou-Thompson D, Wang Y, Griffiths TM, Lee M, Haymaker CL, Dominguez AL, Basar R, Reyes C, Kumar S, Meyer LA, Hwu P, Bernatchez C, Jazaeri AA. Fix SM, et al. Among authors: wang y. J Immunother Cancer. 2022 Jul;10(7):e003750. doi: 10.1136/jitc-2021-003750. J Immunother Cancer. 2022. PMID: 35882447 Free PMC article.
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