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Inducible CRISPR genome editing platform in naive human embryonic stem cells reveals JARID2 function in self-renewal.
Ferreccio A, Mathieu J, Detraux D, Somasundaram L, Cavanaugh C, Sopher B, Fischer K, Bello T, M Hussein A, Levy S, Cook S, Sidhu SB, Artoni F, Palpant NJ, Reinecke H, Wang Y, Paddison P, Murry C, Jayadev S, Ware C, Ruohola-Baker H. Ferreccio A, et al. Among authors: wang y. Cell Cycle. 2018;17(5):535-549. doi: 10.1080/15384101.2018.1442621. Epub 2018 Apr 5. Cell Cycle. 2018. PMID: 29466914 Free PMC article.
The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition.
Sperber H, Mathieu J, Wang Y, Ferreccio A, Hesson J, Xu Z, Fischer KA, Devi A, Detraux D, Gu H, Battle SL, Showalter M, Valensisi C, Bielas JH, Ericson NG, Margaretha L, Robitaille AM, Margineantu D, Fiehn O, Hockenbery D, Blau CA, Raftery D, Margolin AA, Hawkins RD, Moon RT, Ware CB, Ruohola-Baker H. Sperber H, et al. Among authors: wang y. Nat Cell Biol. 2015 Dec;17(12):1523-35. doi: 10.1038/ncb3264. Epub 2015 Nov 16. Nat Cell Biol. 2015. PMID: 26571212 Free PMC article.
Metabolic remodeling in early development and cardiomyocyte maturation.
Ellen Kreipke R, Wang Y, Miklas JW, Mathieu J, Ruohola-Baker H. Ellen Kreipke R, et al. Among authors: wang y. Semin Cell Dev Biol. 2016 Apr;52:84-92. doi: 10.1016/j.semcdb.2016.02.004. Epub 2016 Feb 18. Semin Cell Dev Biol. 2016. PMID: 26912118 Free PMC article. Review.
First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor.
Moody JD, Levy S, Mathieu J, Xing Y, Kim W, Dong C, Tempel W, Robitaille AM, Dang LT, Ferreccio A, Detraux D, Sidhu S, Zhu L, Carter L, Xu C, Valensisi C, Wang Y, Hawkins RD, Min J, Moon RT, Orkin SH, Baker D, Ruohola-Baker H. Moody JD, et al. Among authors: wang y. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10125-10130. doi: 10.1073/pnas.1706907114. Epub 2017 Sep 1. Proc Natl Acad Sci U S A. 2017. PMID: 28864533 Free PMC article.
Human Organ-Specific Endothelial Cell Heterogeneity.
Marcu R, Choi YJ, Xue J, Fortin CL, Wang Y, Nagao RJ, Xu J, MacDonald JW, Bammler TK, Murry CE, Muczynski K, Stevens KR, Himmelfarb J, Schwartz SM, Zheng Y. Marcu R, et al. Among authors: wang y. iScience. 2018 Jun 29;4:20-35. doi: 10.1016/j.isci.2018.05.003. Epub 2018 May 9. iScience. 2018. PMID: 30240741 Free PMC article.
Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation.
Friedman CE, Nguyen Q, Lukowski SW, Helfer A, Chiu HS, Miklas J, Levy S, Suo S, Han JJ, Osteil P, Peng G, Jing N, Baillie GJ, Senabouth A, Christ AN, Bruxner TJ, Murry CE, Wong ES, Ding J, Wang Y, Hudson J, Ruohola-Baker H, Bar-Joseph Z, Tam PPL, Powell JE, Palpant NJ. Friedman CE, et al. Among authors: wang y. Cell Stem Cell. 2018 Oct 4;23(4):586-598.e8. doi: 10.1016/j.stem.2018.09.009. Cell Stem Cell. 2018. PMID: 30290179 Free PMC article.
Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency.
Mathieu J, Detraux D, Kuppers D, Wang Y, Cavanaugh C, Sidhu S, Levy S, Robitaille AM, Ferreccio A, Bottorff T, McAlister A, Somasundaram L, Artoni F, Battle S, Hawkins RD, Moon RT, Ware CB, Paddison PJ, Ruohola-Baker H. Mathieu J, et al. Among authors: wang y. Nat Commun. 2019 Feb 7;10(1):632. doi: 10.1038/s41467-018-08020-0. Nat Commun. 2019. PMID: 30733432 Free PMC article.
Metabolism as an early predictor of DPSCs aging.
Macrin D, Alghadeer A, Zhao YT, Miklas JW, Hussein AM, Detraux D, Robitaille AM, Madan A, Moon RT, Wang Y, Devi A, Mathieu J, Ruohola-Baker H. Macrin D, et al. Among authors: wang y. Sci Rep. 2019 Feb 18;9(1):2195. doi: 10.1038/s41598-018-37489-4. Sci Rep. 2019. PMID: 30778087 Free PMC article.
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