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The role of FXR and TGR5 in reversing and preventing progression of Western diet-induced hepatic steatosis, inflammation, and fibrosis in mice.
Wang XX, Xie C, Libby AE, Ranjit S, Levi J, Myakala K, Bhasin K, Jones BA, Orlicky DJ, Takahashi S, Dvornikov A, Kleiner DE, Hewitt SM, Adorini L, Kopp JB, Krausz KW, Rosenberg A, McManaman JL, Robertson CE, Ir D, Frank DN, Luo Y, Gonzalez FJ, Gratton E, Levi M. Wang XX, et al. J Biol Chem. 2022 Nov;298(11):102530. doi: 10.1016/j.jbc.2022.102530. Epub 2022 Oct 7. J Biol Chem. 2022. PMID: 36209823 Free PMC article.
Nuclear hormone receptors in diabetic nephropathy.
Wang XX, Jiang T, Levi M. Wang XX, et al. Nat Rev Nephrol. 2010 Jun;6(6):342-51. doi: 10.1038/nrneph.2010.56. Epub 2010 Apr 27. Nat Rev Nephrol. 2010. PMID: 20421884 Review.
Diabetic nephropathy is accelerated by farnesoid X receptor deficiency and inhibited by farnesoid X receptor activation in a type 1 diabetes model.
Wang XX, Jiang T, Shen Y, Caldas Y, Miyazaki-Anzai S, Santamaria H, Urbanek C, Solis N, Scherzer P, Lewis L, Gonzalez FJ, Adorini L, Pruzanski M, Kopp JB, Verlander JW, Levi M. Wang XX, et al. Diabetes. 2010 Nov;59(11):2916-27. doi: 10.2337/db10-0019. Epub 2010 Aug 10. Diabetes. 2010. PMID: 20699418 Free PMC article.
Nuclear hormone receptors as therapeutic targets.
Levi M, Wang X, Choudhury D. Levi M, et al. Contrib Nephrol. 2011;170:209-216. doi: 10.1159/000325668. Epub 2011 Jun 9. Contrib Nephrol. 2011. PMID: 21659773 Review.
1,646 results