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A novel semisynthesized small molecule icaritin reduces incidence of steroid-associated osteonecrosis with inhibition of both thrombosis and lipid-deposition in a dose-dependent manner.
Zhang G, Qin L, Sheng H, Wang XL, Wang YX, Yeung DK, Griffith JF, Yao XS, Xie XH, Li ZR, Lee KM, Leung KS. Zhang G, et al. Among authors: wang yx, wang xl. Bone. 2009 Feb;44(2):345-56. doi: 10.1016/j.bone.2008.10.035. Epub 2008 Oct 22. Bone. 2009. PMID: 19015051 Free PMC article.
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