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Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation.
Cell Metab. 2023 Dec 5;35(12):2119-2135.e5. doi: 10.1016/j.cmet.2023.10.003. Epub 2023 Oct 31.
Cell Metab. 2023.
PMID: 37913768
Centrins control chicken cone cell lipid droplet dynamics through lipid-droplet-localized SPDL1.
Pan H, Qin Y, Zhu J, Wang W, Liu Z, Huang X, Lam SM, Shui G, Wang Y, Jiang Y, Huang X.
Pan H, et al.
Dev Cell. 2023 Nov 20;58(22):2528-2544.e8. doi: 10.1016/j.devcel.2023.08.012. Epub 2023 Sep 11.
Dev Cell. 2023.
PMID: 37699389
Free article.
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IGSF8 is an innate immune checkpoint and cancer immunotherapy target.
Li Y, Wu X, Sheng C, Liu H, Liu H, Tang Y, Liu C, Ding Q, Xie B, Xiao X, Zheng R, Yu Q, Guo Z, Ma J, Wang J, Gao J, Tian M, Wang W, Zhou J, Jiang L, Gu M, Shi S, Paull M, Yang G, Yang W, Landau S, Bao X, Hu X, Liu XS, Xiao T.
Li Y, et al.
Cell. 2024 Apr 18:S0092-8674(24)00355-6. doi: 10.1016/j.cell.2024.03.039. Online ahead of print.
Cell. 2024.
PMID: 38657602
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ISG20L1 acts as a co-activator of DAPK1 in the activation of the p53-dependent cell death pathway.
Zou S, Zhang C, Xu H, Liu Z, Hu Y, Wang W, Liu K, Wen Q, Song L.
Zou S, et al.
J Cell Sci. 2023 Apr 1;136(7):jcs260915. doi: 10.1242/jcs.260915. Epub 2023 Mar 27.
J Cell Sci. 2023.
PMID: 36855954
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Noncoding transcripts are linked to brain resting-state activity in non-human primates.
Wang W, Bo T, Zhang G, Li J, Ma J, Ma L, Hu G, Tong H, Lv Q, Araujo DJ, Luo D, Chen Y, Wang M, Wang Z, Wang GZ.
Wang W, et al.
Cell Rep. 2023 Jun 27;42(6):112652. doi: 10.1016/j.celrep.2023.112652. Epub 2023 Jun 18.
Cell Rep. 2023.
PMID: 37335775
Free article.
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Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation.
Jing Y, Jiang X, Ji Q, Wu Z, Wang W, Liu Z, Guillen-Garcia P, Esteban CR, Reddy P, Horvath S, Li J, Geng L, Hu Q, Wang S, Belmonte JCI, Ren J, Zhang W, Qu J, Liu GH.
Jing Y, et al.
Cell Stem Cell. 2023 Nov 2;30(11):1452-1471.e10. doi: 10.1016/j.stem.2023.09.007. Epub 2023 Oct 12.
Cell Stem Cell. 2023.
PMID: 37832549
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RNF144B-mediated p21 degradation regulated by HDAC3 contribute to enhancing ovarian cancer growth and metastasis.
Zhuang H, Zhang Z, Wang W, Qu H.
Zhuang H, et al.
Tissue Cell. 2024 Feb;86:102277. doi: 10.1016/j.tice.2023.102277. Epub 2023 Nov 19.
Tissue Cell. 2024.
PMID: 37992458
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