Wang WC - Search Results

1

Small-molecule EGFR tyrosine kinase inhibitors for the treatment of cancer.

Lee CC, Shiao HY, Wang WC, Hsieh HP. Lee CC, et al. Among authors: wang wc. Expert Opin Investig Drugs. 2014 Oct;23(10):1333-48. doi: 10.1517/13543784.2014.928283. Epub 2014 Jun 12. Expert Opin Investig Drugs. 2014. PMID: 24921970 Review.

2

3D-QSAR-assisted drug design: identification of a potent quinazoline-based Aurora kinase inhibitor.

Ke YY, Shiao HY, Hsu YC, Chu CY, Wang WC, Lee YC, Lin WH, Chen CH, Hsu JT, Chang CW, Lin CW, Yeh TK, Chao YS, Coumar MS, Hsieh HP. Ke YY, et al. Among authors: wang wc. ChemMedChem. 2013 Jan;8(1):136-48. doi: 10.1002/cmdc.201200464. Epub 2012 Nov 22. ChemMedChem. 2013. PMID: 23172777

3

Ligand efficiency based approach for efficient virtual screening of compound libraries.

Ke YY, Coumar MS, Shiao HY, Wang WC, Chen CW, Song JS, Chen CH, Lin WH, Wu SH, Hsu JT, Chang CM, Hsieh HP. Ke YY, et al. Among authors: wang wc. Eur J Med Chem. 2014 Aug 18;83:226-35. doi: 10.1016/j.ejmech.2014.06.029. Epub 2014 Jun 14. Eur J Med Chem. 2014. PMID: 24960626

4

Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification.

Ke YY, Singh VK, Coumar MS, Hsu YC, Wang WC, Song JS, Chen CH, Lin WH, Wu SH, Hsu JT, Shih C, Hsieh HP. Ke YY, et al. Among authors: wang wc. Sci Rep. 2015 Jun 29;5:11702. doi: 10.1038/srep11702. Sci Rep. 2015. PMID: 26118648 Free PMC article.

5

Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design.

Chang CF, Lin WH, Ke YY, Lin YS, Wang WC, Chen CH, Kuo PC, Hsu JTA, Uang BJ, Hsieh HP. Chang CF, et al. Among authors: wang wc. Eur J Med Chem. 2016 Nov 29;124:186-199. doi: 10.1016/j.ejmech.2016.08.026. Epub 2016 Aug 16. Eur J Med Chem. 2016. PMID: 27573544

6

Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation.

Hsu YC, Coumar MS, Wang WC, Shiao HY, Ke YY, Lin WH, Kuo CC, Chang CW, Kuo FM, Chen PY, Wang SY, Li AS, Chen CH, Kuo PC, Chen CP, Wu MH, Huang CL, Yen KJ, Chang YI, Hsu JT, Chen CT, Yeh TK, Song JS, Shih C, Hsieh HP. Hsu YC, et al. Among authors: wang wc, wang sy. Oncotarget. 2016 Dec 27;7(52):86239-86256. doi: 10.18632/oncotarget.13369. Oncotarget. 2016. PMID: 27863392 Free PMC article.

7

Discovery of an Orally Efficacious MYC Inhibitor for Liver Cancer Using a GNMT-Based High-Throughput Screening System and Structure-Activity Relationship Analysis.

Kant R, Yang MH, Tseng CH, Yen CH, Li WY, Tyan YC, Chen M, Tzeng CC, Chen WC, You K, Wang WC, Chen YL, Chen YA. Kant R, et al. Among authors: wang wc. J Med Chem. 2021 Jul 8;64(13):8992-9009. doi: 10.1021/acs.jmedchem.1c00093. Epub 2021 Jun 16. J Med Chem. 2021. PMID: 34132534

8

Structural basis and synergism of ATP and Na⁺ activation in bacterial K⁺ uptake system KtrAB.

Chiang WT, Chang YK, Hui WH, Chang SW, Liao CY, Chang YC, Chen CJ, Wang WC, Lai CC, Wang CH, Luo SY, Huang YP, Chou SH, Horng TL, Hou MH, Muench SP, Chen RS, Tsai MD, Hu NJ. Chiang WT, et al. Among authors: wang wc. Nat Commun. 2024 May 8;15(1):3850. doi: 10.1038/s41467-024-48057-y. Nat Commun. 2024. PMID: 38719864 Free PMC article.

9

Metabolomics facilitates differential diagnosis in common inherited retinal degenerations by exploring their profiles of serum metabolites.

Wang WC, Huang CH, Chung HH, Chen PL, Hu FR, Yang CH, Yang CM, Lin CW, Hsu CC, Chen TC. Wang WC, et al. Nat Commun. 2024 Apr 26;15(1):3562. doi: 10.1038/s41467-024-47911-3. Nat Commun. 2024. PMID: 38670966 Free PMC article.

10

Effects of fermented cottonseed meal inclusions on growth performance, serum biochemical parameters and hepatic lipid metabolism of geese during 28-70 d of age.

Xie SS, Shen JJ, Liu Y, Yang ZL, Wang WC, Yang L, Zhu YW. Xie SS, et al. Among authors: wang wc. Poult Sci. 2024 Apr 1;103(6):103702. doi: 10.1016/j.psj.2024.103702. Online ahead of print. Poult Sci. 2024. PMID: 38652950 Free PMC article.

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