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ChAdOx1 nCoV-19 (AZD1222) vaccine-induced Fc receptor binding tracks with differential susceptibility to COVID-19.
Kaplonek P, Cizmeci D, Kwatra G, Izu A, Lee JS, Bertera HL, Fischinger S, Mann C, Amanat F, Wang W, Koen AL, Fairlie L, Cutland CL, Ahmed K, Dheda K, Barnabas SL, Bhorat QE, Briner C, Krammer F, Saphire EO, Gilbert SC, Lambe T, Pollard AJ, Nunes M, Wuhrer M, Lauffenburger DA, Madhi SA, Alter G. Kaplonek P, et al. Among authors: wang w. Nat Immunol. 2023 Jul;24(7):1161-1172. doi: 10.1038/s41590-023-01513-1. Epub 2023 Jun 15. Nat Immunol. 2023. PMID: 37322179 Free PMC article.
Immunoglobulin G1 Fc glycosylation as an early hallmark of severe COVID-19.
Pongracz T, Nouta J, Wang W, van Meijgaarden KE, Linty F, Vidarsson G, Joosten SA, Ottenhoff THM, Hokke CH, de Vries JJC, Arbous SM, Roukens AHE, Wuhrer M; BEAT-COVID; COVID-19 groups. Pongracz T, et al. Among authors: wang w. EBioMedicine. 2022 Apr;78:103957. doi: 10.1016/j.ebiom.2022.103957. Epub 2022 Mar 22. EBioMedicine. 2022. PMID: 35334306 Free PMC article.
mRNA vaccines against SARS-CoV-2 induce comparably low long-term IgG Fc galactosylation and sialylation levels but increasing long-term IgG4 responses compared to an adenovirus-based vaccine.
Buhre JS, Pongracz T, Künsting I, Lixenfeld AS, Wang W, Nouta J, Lehrian S, Schmelter F, Lunding HB, Dühring L, Kern C, Petry J, Martin EL, Föh B, Steinhaus M, von Kopylow V, Sina C, Graf T, Rahmöller J, Wuhrer M, Ehlers M. Buhre JS, et al. Among authors: wang w. Front Immunol. 2023 Jan 12;13:1020844. doi: 10.3389/fimmu.2022.1020844. eCollection 2022. Front Immunol. 2023. PMID: 36713457 Free PMC article.
IgG1 glycosylation highlights premature aging in Down syndrome.
Streng BMM, Van Coillie J, Wildenbeest JG, Binnendijk RS, Smits G, den Hartog G, Wang W, Nouta J, Linty F, Visser R, Wuhrer M, Vidarsson G, Bont LJ; PRIDE study group. Streng BMM, et al. Among authors: wang w. Aging Cell. 2024 Apr 15:e14167. doi: 10.1111/acel.14167. Online ahead of print. Aging Cell. 2024. PMID: 38616780 Free article.
The IgG glycome of SARS-CoV-2 infected individuals reflects disease course and severity.
Siekman SL, Pongracz T, Wang W, Nouta J, Kremsner PG, da Silva-Neto PV, Esen M, Kreidenweiss A, Held J, Trapé ÁA, Fendel R, de Miranda Santos IKF, Wuhrer M; ImmunoCovid Consortium. Siekman SL, et al. Among authors: wang w. Front Immunol. 2022 Oct 18;13:993354. doi: 10.3389/fimmu.2022.993354. eCollection 2022. Front Immunol. 2022. PMID: 36389824 Free PMC article.
Analysis of Immunogenic Galactose-α-1,3-galactose-Containing N-Glycans in Beef, Mutton, and Pork Tenderloin by Combining Matrix-Assisted Laser Desorption/Ionization-Mass Spectroscopy and Capillary Electrophoresis Hyphenated with Mass Spectrometry via Electrospray Ionization.
Guo RR, Lageveen-Kammeijer GSM, Wang W, Dalebout H, Zhang W, Wuhrer M, Liu L, Heijs B, Voglmeir J. Guo RR, et al. Among authors: wang w. J Agric Food Chem. 2023 Mar 8;71(9):4184-4192. doi: 10.1021/acs.jafc.2c08067. Epub 2023 Feb 21. J Agric Food Chem. 2023. PMID: 36809004
Comparative analysis of spike-specific IgG Fc glycoprofiles elicited by adenoviral, mRNA, and protein-based SARS-CoV-2 vaccines.
Van Coillie J, Pongracz T, Šuštić T, Wang W, Nouta J, Le Gars M, Keijzer S, Linty F, Cristianawati O, Keijser JBD, Visser R, van Vught LA, Slim MA, van Mourik N, Smit MJ, Sander A, Schmidt DE, Steenhuis M, Rispens T, Nielsen MA, Mordmüller BG, Vlaar APJ, Ellen van der Schoot C, Roozendaal R, Wuhrer M, Vidarsson G; UMC COVID-19 S3/HCW study group; Fatebenefratelli-Sacco Infectious Diseases Physicians group; Radboud University Medical Center (RUMC) and COUGH1 study group. Van Coillie J, et al. Among authors: wang w. iScience. 2023 Aug 14;26(9):107619. doi: 10.1016/j.isci.2023.107619. eCollection 2023 Sep 15. iScience. 2023. PMID: 37670790 Free PMC article.
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