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BRSK2 in pancreatic β cells promotes hyperinsulinemia-coupled insulin resistance and its genetic variants are associated with human type 2 diabetes.
Xu R, Wang K, Yao Z, Zhang Y, Jin L, Pang J, Zhou Y, Wang K, Liu D, Zhang Y, Sun P, Wang F, Chang X, Liu T, Wang S, Zhang Y, Lin S, Hu C, Zhu Y, Han X. Xu R, et al. Among authors: wang f, wang k, wang s. J Mol Cell Biol. 2023 Nov 27;15(5):mjad033. doi: 10.1093/jmcb/mjad033. J Mol Cell Biol. 2023. PMID: 37188647 Free PMC article.
Galectin-3 impairs calcium transients and β-cell function.
Jiang Q, Zhao Q, Chen Y, Ma C, Peng X, Wu X, Liu X, Wang R, Hou S, Kong L, Wan Y, Wang S, Meng ZX, Cui B, Chen L, Li P. Jiang Q, et al. Among authors: wang s, wang r. Nat Commun. 2024 May 1;15(1):3682. doi: 10.1038/s41467-024-47959-1. Nat Commun. 2024. PMID: 38693121 Free PMC article.
IER3IP1 is critical for maintaining glucose homeostasis through regulating the endoplasmic reticulum function and survival of β cells.
Yang J, Zhen J, Feng W, Fan Z, Ding L, Yang X, Huang Y, Shu H, Xie J, Li X, Qiao J, Fan Y, Sun J, Li N, Liu T, Wang S, Zhang X, Arvan P, Liu M. Yang J, et al. Among authors: wang s. Proc Natl Acad Sci U S A. 2022 Nov 8;119(45):e2204443119. doi: 10.1073/pnas.2204443119. Epub 2022 Nov 2. Proc Natl Acad Sci U S A. 2022. PMID: 36322741 Free PMC article.
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