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New Antibiotic Candidates against Helicobacter pylori.
Wang S, Cameron SA, Clinch K, Evans GB, Wu Z, Schramm VL, Tyler PC. Wang S, et al. J Am Chem Soc. 2015 Nov 18;137(45):14275-80. doi: 10.1021/jacs.5b06110. Epub 2015 Nov 9. J Am Chem Soc. 2015. PMID: 26494017 Free PMC article.
H. pylori uses an unusual pathway for menaquinone biosynthesis with 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTAN) catalyzing an essential step. We validated MTAN as a target with a transition-state analogue of the enzyme [Wang, S.; Haapala …
H. pylori uses an unusual pathway for menaquinone biosynthesis with 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTAN) …
Overlapping hotspots in CDRs are critical sites for V region diversification.
Wei L, Chahwan R, Wang S, Wang X, Pham PT, Goodman MF, Bergman A, Scharff MD, MacCarthy T. Wei L, et al. Among authors: wang x, wang s. Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E728-37. doi: 10.1073/pnas.1500788112. Epub 2015 Feb 2. Proc Natl Acad Sci U S A. 2015. PMID: 25646473 Free PMC article.
Recent insights about autophagy in pancreatitis.
Ding WX, Ma X, Kim S, Wang S, Ni HM. Ding WX, et al. Among authors: wang s. eGastroenterology. 2024 Apr;2(2):e100057. doi: 10.1136/egastro-2023-100057. Epub 2024 May 3. eGastroenterology. 2024. PMID: 38770349 Free PMC article.
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