Wang P - Search Results

1

Augmented Stat5 Signaling Bypasses Multiple Impediments to Lactogen-Mediated Proliferation in Human β-Cells.

Chen H, Kleinberger JW, Takane KK, Salim F, Fiaschi-Taesch N, Pappas K, Parsons R, Jiang J, Zhang Y, Liu H, Wang P, Bender AS, Frank SJ, Stewart AF. Chen H, et al. Among authors: wang p. Diabetes. 2015 Nov;64(11):3784-97. doi: 10.2337/db15-0083. Epub 2015 Jul 9. Diabetes. 2015. PMID: 26159175 Free PMC article.

2

Diabetes mellitus--advances and challenges in human β-cell proliferation.

Wang P, Fiaschi-Taesch NM, Vasavada RC, Scott DK, García-Ocaña A, Stewart AF. Wang P, et al. Nat Rev Endocrinol. 2015 Apr;11(4):201-12. doi: 10.1038/nrendo.2015.9. Epub 2015 Feb 17. Nat Rev Endocrinol. 2015. PMID: 25687999 Review.

3

A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.

Wang P, Alvarez-Perez JC, Felsenfeld DP, Liu H, Sivendran S, Bender A, Kumar A, Sanchez R, Scott DK, Garcia-Ocaña A, Stewart AF. Wang P, et al. Nat Med. 2015 Apr;21(4):383-8. doi: 10.1038/nm.3820. Epub 2015 Mar 9. Nat Med. 2015. PMID: 25751815 Free PMC article.

4

Definition of a Skp2-c-Myc Pathway to Expand Human Beta-cells.

Tiwari S, Roel C, Tanwir M, Wills R, Perianayagam N, Wang P, Fiaschi-Taesch NM. Tiwari S, et al. Among authors: wang p. Sci Rep. 2016 Jul 6;6:28461. doi: 10.1038/srep28461. Sci Rep. 2016. PMID: 27380896 Free PMC article.

5

Development of a reliable automated screening system to identify small molecules and biologics that promote human β-cell regeneration.

Aamodt KI, Aramandla R, Brown JJ, Fiaschi-Taesch N, Wang P, Stewart AF, Brissova M, Powers AC. Aamodt KI, et al. Among authors: wang p. Am J Physiol Endocrinol Metab. 2016 Nov 1;311(5):E859-E868. doi: 10.1152/ajpendo.00515.2015. Epub 2016 Sep 13. Am J Physiol Endocrinol Metab. 2016. PMID: 27624103 Free PMC article.

6

Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas.

Wang H, Bender A, Wang P, Karakose E, Inabnet WB, Libutti SK, Arnold A, Lambertini L, Stang M, Chen H, Kasai Y, Mahajan M, Kinoshita Y, Fernandez-Ranvier G, Becker TC, Takane KK, Walker LA, Saul S, Chen R, Scott DK, Ferrer J, Antipin Y, Donovan M, Uzilov AV, Reva B, Schadt EE, Losic B, Argmann C, Stewart AF. Wang H, et al. Among authors: wang p. Nat Commun. 2017 Oct 3;8(1):767. doi: 10.1038/s41467-017-00992-9. Nat Commun. 2017. PMID: 28974674 Free PMC article.

7

Cell-Based Methods to Identify Inducers of Human Pancreatic Beta-Cell Proliferation.

Ackeifi CA, Swartz EA, Wang P. Ackeifi CA, et al. Among authors: wang p. Methods Mol Biol. 2018;1787:87-100. doi: 10.1007/978-1-4939-7847-2_7. Methods Mol Biol. 2018. PMID: 29736712

8

Advances in drug discovery for human beta cell regeneration.

Karakose E, Ackeifi C, Wang P, Stewart AF. Karakose E, et al. Among authors: wang p. Diabetologia. 2018 Aug;61(8):1693-1699. doi: 10.1007/s00125-018-4639-6. Epub 2018 May 16. Diabetologia. 2018. PMID: 29770834 Free PMC article. Review.

9

Development of Kinase-Selective, Harmine-Based DYRK1A Inhibitors that Induce Pancreatic Human β-Cell Proliferation.

Kumar K, Wang P, Sanchez R, Swartz EA, Stewart AF, DeVita RJ. Kumar K, et al. Among authors: wang p. J Med Chem. 2018 Sep 13;61(17):7687-7699. doi: 10.1021/acs.jmedchem.8b00658. Epub 2018 Aug 21. J Med Chem. 2018. PMID: 30059217 Free PMC article.

10

Novel selective thiadiazine DYRK1A inhibitor lead scaffold with human pancreatic β-cell proliferation activity.

Kumar K, Man-Un Ung P, Wang P, Wang H, Li H, Andrews MK, Stewart AF, Schlessinger A, DeVita RJ. Kumar K, et al. Among authors: wang h, wang p. Eur J Med Chem. 2018 Sep 5;157:1005-1016. doi: 10.1016/j.ejmech.2018.08.007. Epub 2018 Aug 22. Eur J Med Chem. 2018. PMID: 30170319 Free PMC article.

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