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Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition.
Liu CC, Hu J, Zhao N, Wang J, Wang N, Cirrito JR, Kanekiyo T, Holtzman DM, Bu G. Liu CC, et al. Among authors: wang j, wang n. J Neurosci. 2017 Apr 12;37(15):4023-4031. doi: 10.1523/JNEUROSCI.3442-16.2017. Epub 2017 Mar 8. J Neurosci. 2017. PMID: 28275161 Free PMC article.
ApoE4 Accelerates Early Seeding of Amyloid Pathology.
Liu CC, Zhao N, Fu Y, Wang N, Linares C, Tsai CW, Bu G. Liu CC, et al. Among authors: wang n. Neuron. 2017 Dec 6;96(5):1024-1032.e3. doi: 10.1016/j.neuron.2017.11.013. Neuron. 2017. PMID: 29216449 Free PMC article.
Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model.
Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, Wang D, Gao Y, Zhu Y, Sheng X, Chen K, Wang N, Zhu L, Can D, Marten Y, Shinohara M, Liu CC, Du D, Sun H, Wen L, Xu H, Bu G, Chen XF. Zhong L, et al. Among authors: wang k, wang n, wang t, wang d. Nat Commun. 2019 Mar 25;10(1):1365. doi: 10.1038/s41467-019-09118-9. Nat Commun. 2019. PMID: 30911003 Free PMC article.
Author Correction: Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model.
Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, Wang D, Gao Y, Zhu Y, Sheng X, Chen K, Wang N, Zhu L, Can D, Marten Y, Shinohara M, Liu CC, Du D, Sun H, Wen L, Xu H, Bu G, Chen XF. Zhong L, et al. Among authors: wang k, wang n, wang t, wang d. Nat Commun. 2019 Jul 2;10(1):2923. doi: 10.1038/s41467-019-10950-2. Nat Commun. 2019. PMID: 31266955 Free PMC article.
Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aβ42 in triggering receptor expressed on myeloid cells 2 loss-of-function murine models.
Rong Z, Cheng B, Zhong L, Ye X, Li X, Jia L, Li Y, Shue F, Wang N, Cheng Y, Huang X, Liu CC, Fryer JD, Wang X, Zhang YW, Zheng H. Rong Z, et al. Among authors: wang x, wang n. FASEB J. 2020 Aug;34(8):10984-10997. doi: 10.1096/fj.202000550RR. Epub 2020 Jul 1. FASEB J. 2020. PMID: 32613609
Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer's disease.
Liu CC, Yamazaki Y, Heckman MG, Martens YA, Jia L, Yamazaki A, Diehl NN, Zhao J, Zhao N, DeTure M, Davis MD, Felton LM, Qiao W, Li Y, Li H, Fu Y, Wang N, Wren M, Aikawa T, Holm ML, Oue H, Linares C, Allen M, Carrasquillo MM, Murray ME, Petersen RC, Ertekin-Taner N, Dickson DW, Kanekiyo T, Bu G. Liu CC, et al. Among authors: wang n. Alzheimers Dement. 2020 Oct;16(10):1372-1383. doi: 10.1002/alz.12104. Epub 2020 Aug 22. Alzheimers Dement. 2020. PMID: 32827351 Free PMC article.
APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia.
Liu CC, Murray ME, Li X, Zhao N, Wang N, Heckman MG, Shue F, Martens Y, Li Y, Raulin AC, Rosenberg CL, Doss SV, Zhao J, Wren MC, Jia L, Ren Y, Ikezu TC, Lu W, Fu Y, Caulfield T, Trottier ZA, Knight J, Chen Y, Linares C, Wang X, Kurti A, Asmann YW, Wszolek ZK, Smith GE, Vemuri P, Kantarci K, Knopman DS, Lowe VJ, Jack CR Jr, Parisi JE, Ferman TJ, Boeve BF, Graff-Radford NR, Petersen RC, Younkin SG, Fryer JD, Wang H, Han X, Frieden C, Dickson DW, Ross OA, Bu G. Liu CC, et al. Among authors: wang x, wang h, wang n. Sci Transl Med. 2021 Sep 29;13(613):eabc9375. doi: 10.1126/scitranslmed.abc9375. Epub 2021 Sep 29. Sci Transl Med. 2021. PMID: 34586832 Free PMC article.
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