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Hyperleptinemia contributes to antipsychotic drug-associated obesity and metabolic disorders.
Zhao S, Lin Q, Xiong W, Li L, Straub L, Zhang D, Zapata R, Zhu Q, Sun XN, Zhang Z, Funcke JB, Li C, Chen S, Zhu Y, Jiang N, Li G, Xu Z, Wyler SC, Wang MY, Bai J, Han X, Kusminski CM, Zhang N, An Z, Elmquist JK, Osborn O, Liu C, Scherer PE. Zhao S, et al. Among authors: wang my. Sci Transl Med. 2023 Nov 22;15(723):eade8460. doi: 10.1126/scitranslmed.ade8460. Epub 2023 Nov 22. Sci Transl Med. 2023. PMID: 37992151
Glucagon therapeutics: Dawn of a new era for diabetes care.
Davidson JA, Holland WL, Roth MG, Wang MY, Lee Y, Yu X, McCorkle SK, Scherer PE, Unger RH. Davidson JA, et al. Among authors: wang my. Diabetes Metab Res Rev. 2016 Oct;32(7):660-665. doi: 10.1002/dmrr.2773. Epub 2016 Feb 7. Diabetes Metab Res Rev. 2016. PMID: 26729301 Review.
Dapagliflozin suppresses glucagon signaling in rodent models of diabetes.
Wang MY, Yu X, Lee Y, McCorkle SK, Chen S, Li J, Wang ZV, Davidson JA, Scherer PE, Holland WL, Unger RH, Roth MG. Wang MY, et al. Among authors: wang zv. Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):6611-6616. doi: 10.1073/pnas.1705845114. Epub 2017 Jun 5. Proc Natl Acad Sci U S A. 2017. PMID: 28584109 Free PMC article.
Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice.
Zhang Z, Shao M, Hepler C, Zi Z, Zhao S, An YA, Zhu Y, Ghaben AL, Wang MY, Li N, Onodera T, Joffin N, Crewe C, Zhu Q, Vishvanath L, Kumar A, Xing C, Wang QA, Gautron L, Deng Y, Gordillo R, Kruglikov I, Kusminski CM, Gupta RK, Scherer PE. Zhang Z, et al. Among authors: wang my, wang qa. J Clin Invest. 2019 Dec 2;129(12):5327-5342. doi: 10.1172/JCI130239. J Clin Invest. 2019. PMID: 31503545 Free PMC article.
Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets.
Wang MY, Dean ED, Quittner-Strom E, Zhu Y, Chowdhury KH, Zhang Z, Zhao S, Li N, Ye R, Lee Y, Zhang Y, Chen S, Yu X, Leonard DC, Poffenberger G, Von Deylen A, McCorkle SK, Schlegel A, Sloop KW, Efanov AM, Gimeno RE, Scherer PE, Powers AC, Unger RH, Holland WL. Wang MY, et al. Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2022142118. doi: 10.1073/pnas.2022142118. Proc Natl Acad Sci U S A. 2021. PMID: 33619103 Free PMC article.
Adiponectin preserves metabolic fitness during aging.
Li N, Zhao S, Zhang Z, Zhu Y, Gliniak CM, Vishvanath L, An YA, Wang MY, Deng Y, Zhu Q, Shan B, Sherwood A, Onodera T, Oz OK, Gordillo R, Gupta RK, Liu M, Horvath TL, Dixit VD, Scherer PE. Li N, et al. Among authors: wang my. Elife. 2021 Apr 27;10:e65108. doi: 10.7554/eLife.65108. Elife. 2021. PMID: 33904399 Free PMC article.
Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity.
Zhang Z, Funcke JB, Zi Z, Zhao S, Straub LG, Zhu Y, Zhu Q, Crewe C, An YA, Chen S, Li N, Wang MY, Ghaben AL, Lee C, Gautron L, Engelking LJ, Raj P, Deng Y, Gordillo R, Kusminski CM, Scherer PE. Zhang Z, et al. Among authors: wang my. Cell Metab. 2021 Aug 3;33(8):1624-1639.e9. doi: 10.1016/j.cmet.2021.06.001. Epub 2021 Jun 25. Cell Metab. 2021. PMID: 34174197 Free PMC article.
1,945 results