Wang LX - Search Results

1

Implementation of Glycan Remodeling to Plant-Made Therapeutic Antibodies.

Bennett LD, Yang Q, Berquist BR, Giddens JP, Ren Z, Kommineni V, Murray RP, White EL, Holtz BR, Wang LX, Marcel S. Bennett LD, et al. Among authors: wang lx. Int J Mol Sci. 2018 Jan 31;19(2):421. doi: 10.3390/ijms19020421. Int J Mol Sci. 2018. PMID: 29385073 Free PMC article.

2

Expression, glycoform characterization, and antibody-binding of HIV-1 V3 glycopeptide domain fused with human IgG1-Fc.

Yang Q, Li C, Wei Y, Huang W, Wang LX. Yang Q, et al. Among authors: wang lx. Bioconjug Chem. 2010 May 19;21(5):875-83. doi: 10.1021/bc9004238. Bioconjug Chem. 2010. PMID: 20369886 Free PMC article.

3

Arthrobacter endo-beta-N-acetylglucosaminidase shows transglycosylation activity on complex-type N-glycan oxazolines: one-pot conversion of ribonuclease B to sialylated ribonuclease C.

Huang W, Yang Q, Umekawa M, Yamamoto K, Wang LX. Huang W, et al. Among authors: wang lx. Chembiochem. 2010 Jul 5;11(10):1350-5. doi: 10.1002/cbic.201000242. Chembiochem. 2010. PMID: 20486148 Free PMC article.

4

Chemoenzymatic synthesis and Fcγ receptor binding of homogeneous glycoforms of antibody Fc domain. Presence of a bisecting sugar moiety enhances the affinity of Fc to FcγIIIa receptor.

Zou G, Ochiai H, Huang W, Yang Q, Li C, Wang LX. Zou G, et al. Among authors: wang lx. J Am Chem Soc. 2011 Nov 23;133(46):18975-91. doi: 10.1021/ja208390n. Epub 2011 Nov 1. J Am Chem Soc. 2011. PMID: 22004528 Free PMC article.

5

Chemoenzymatic glycoengineering of intact IgG antibodies for gain of functions.

Huang W, Giddens J, Fan SQ, Toonstra C, Wang LX. Huang W, et al. Among authors: wang lx. J Am Chem Soc. 2012 Jul 25;134(29):12308-18. doi: 10.1021/ja3051266. Epub 2012 Jul 16. J Am Chem Soc. 2012. PMID: 22747414 Free PMC article.

6

Chemoenzymatic Fc glycosylation via engineered aldehyde tags.

Smith EL, Giddens JP, Iavarone AT, Godula K, Wang LX, Bertozzi CR. Smith EL, et al. Among authors: wang lx. Bioconjug Chem. 2014 Apr 16;25(4):788-95. doi: 10.1021/bc500061s. Epub 2014 Apr 7. Bioconjug Chem. 2014. PMID: 24702330 Free PMC article.

7

Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies.

Trastoy B, Lomino JV, Pierce BG, Carter LG, Günther S, Giddens JP, Snyder GA, Weiss TM, Weng Z, Wang LX, Sundberg EJ. Trastoy B, et al. Among authors: wang lx. Proc Natl Acad Sci U S A. 2014 May 6;111(18):6714-9. doi: 10.1073/pnas.1322908111. Epub 2014 Apr 21. Proc Natl Acad Sci U S A. 2014. PMID: 24753590 Free PMC article.

8

Structural characterization of anti-inflammatory immunoglobulin G Fc proteins.

Ahmed AA, Giddens J, Pincetic A, Lomino JV, Ravetch JV, Wang LX, Bjorkman PJ. Ahmed AA, et al. Among authors: wang lx. J Mol Biol. 2014 Sep 9;426(18):3166-3179. doi: 10.1016/j.jmb.2014.07.006. Epub 2014 Jul 15. J Mol Biol. 2014. PMID: 25036289 Free PMC article.

9

Chemoenzymatic Glyco-engineering of Monoclonal Antibodies.

Giddens JP, Wang LX. Giddens JP, et al. Among authors: wang lx. Methods Mol Biol. 2015;1321:375-87. doi: 10.1007/978-1-4939-2760-9_25. Methods Mol Biol. 2015. PMID: 26082235 Free PMC article.

10

Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity.

Quast I, Keller CW, Maurer MA, Giddens JP, Tackenberg B, Wang LX, Münz C, Nimmerjahn F, Dalakas MC, Lünemann JD. Quast I, et al. Among authors: wang lx. J Clin Invest. 2015 Nov 2;125(11):4160-70. doi: 10.1172/JCI82695. Epub 2015 Oct 5. J Clin Invest. 2015. PMID: 26436649 Free PMC article. Clinical Trial.

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