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ROBO1 deficiency impairs HSPC homeostasis and erythropoiesis via CDC42 and predicts poor prognosis in MDS.
Jin JC, Chen BY, Deng CH, Chen JN, Xu F, Tao Y, Hu CL, Xu CH, Chang BH, Wang Y, Fei MY, Liu P, Yu PC, Li ZJ, Li XY, Chen SB, Jiang YL, Chen XC, Zong LJ, Zhang JY, Ren YY, Xu FH, Liu Q, Huang XH, Guo J, He Q, Song LX, Zhou LY, Su JY, Xiao C, Zhang YM, Yan M, Zhang Z, Wu D, Chang CK, Li X, Wang L, Wu LY. Jin JC, et al. Among authors: wang l, wang y. Sci Adv. 2023 Dec;9(48):eadi7375. doi: 10.1126/sciadv.adi7375. Epub 2023 Nov 29. Sci Adv. 2023. PMID: 38019913 Free article.
Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia.
Hu CL, Chen BY, Li Z, Yang T, Xu CH, Yang R, Yu PC, Zhao J, Liu T, Liu N, Shan B, Zhang Q, Song J, Fei MY, Zong LJ, Zhang JY, Wu JC, Chen SB, Wang Y, Chang B, Hou D, Liu P, Jiang Y, Li X, Chen X, Deng CH, Ren YY, Wang R, Jin J, Xue K, Zhang Y, Du M, Shi J, Wu LY, Chang CK, Shen S, Chen Z, Chen SJ, Liu X, Sun XJ, Zheng M, Wang L. Hu CL, et al. Among authors: wang l, wang y, wang r. Cell Res. 2022 Dec;32(12):1105-1123. doi: 10.1038/s41422-022-00735-6. Epub 2022 Oct 27. Cell Res. 2022. PMID: 36302855 Free PMC article.
STING activation in TET2-mutated hematopoietic stem/progenitor cells contributes to the increased self-renewal and neoplastic transformation.
Xie J, Sheng M, Rong S, Zhou D, Wang C, Wu W, Huang J, Sun Y, Wang Y, Chen P, Wu Y, Wang Y, Wang L, Zhou BO, Huang X, Walsh CP, Bohlander SK, Huang J, Wang X, Xu GL, Gao H, Shi Y. Xie J, et al. Among authors: wang x, wang l, wang y, wang c. Leukemia. 2023 Dec;37(12):2457-2467. doi: 10.1038/s41375-023-02055-z. Epub 2023 Oct 10. Leukemia. 2023. PMID: 37816954 Free PMC article.
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