Wang L - Search Results

1

Discovery of IHMT-MST1-39 as a novel MST1 kinase inhibitor and AMPK activator for the treatment of diabetes mellitus.

Wang J, Qi Z, Wu Y, Wang A, Liu Q, Zou F, Wang B, Qi S, Cao J, Hu C, Shi C, Liang Q, Wang L, Liu J, Wang W, Liu Q. Wang J, et al. Among authors: wang w, wang l, wang b, wang a. Signal Transduct Target Ther. 2023 Apr 5;8(1):143. doi: 10.1038/s41392-023-01352-4. Signal Transduct Target Ther. 2023. PMID: 37015918 Free PMC article.

2

Exploration of type II binding mode: A privileged approach for kinase inhibitor focused drug discovery?

Zhao Z, Wu H, Wang L, Liu Y, Knapp S, Liu Q, Gray NS. Zhao Z, et al. Among authors: wang l. ACS Chem Biol. 2014 Jun 20;9(6):1230-41. doi: 10.1021/cb500129t. Epub 2014 Apr 29. ACS Chem Biol. 2014. PMID: 24730530 Free PMC article. Review.

3

Gliosarcoma: The Distinct Genomic Alterations Identified by Comprehensive Analysis of Copy Number Variations.

Cheng CD, Chen C, Wang L, Dong YF, Yang Y, Chen YN, Niu WX, Wang WC, Liu QS, Niu CS. Cheng CD, et al. Among authors: wang wc, wang l. Anal Cell Pathol (Amst). 2022 Jun 15;2022:2376288. doi: 10.1155/2022/2376288. eCollection 2022. Anal Cell Pathol (Amst). 2022. PMID: 35757013 Free PMC article.

4

Discovery of a highly potent pan-RAF inhibitor IHMT-RAF-128 for cancer treatment.

Wang A, Liu J, Li X, Zou F, Qi Z, Qi S, Liu Q, Wang Z, Cao J, Jiang Z, Wang B, Ge J, Wang L, Wang W, Liu J, Liu Q. Wang A, et al. Among authors: wang w, wang l, wang z, wang b. Eur J Pharmacol. 2023 Aug 5;952:175752. doi: 10.1016/j.ejphar.2023.175752. Epub 2023 May 8. Eur J Pharmacol. 2023. PMID: 37164118

5

Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy.

Hu C, Shen L, Zou F, Wu Y, Wang B, Wang A, Wu C, Wang L, Liu J, Wang W, Liu Q. Hu C, et al. Among authors: wang w, wang l, wang b, wang a. Acta Pharm Sin B. 2023 Sep;13(9):3694-3707. doi: 10.1016/j.apsb.2023.05.026. Epub 2023 May 26. Acta Pharm Sin B. 2023. PMID: 37719386 Free PMC article.

6

Self-Reporting and Splitting Nanopomegranates Potentiate Deep Tissue Cancer Radiotherapy via Elevated Diffusion and Transcytosis.

Wang L, Jiang W, Xiao L, Li H, Chen Z, Liu Y, Dou J, Li S, Wang Q, Han W, Wang Y, Liu H. Wang L, et al. Among authors: wang y, wang q. ACS Nano. 2020 Jul 28;14(7):8459-8472. doi: 10.1021/acsnano.0c02674. Epub 2020 Jul 7. ACS Nano. 2020. PMID: 32598139

7

Inhibitors of the Hippo Pathway Kinases STK3/MST2 and STK4/MST1 Have Utility for the Treatment of Acute Myeloid Leukemia.

Bata N, Chaikuad A, Bakas NA, Limpert AS, Lambert LJ, Sheffler DJ, Berger LM, Liu G, Yuan C, Wang L, Peng Y, Dong J, Celeridad M, Layng F, Knapp S, Cosford NDP. Bata N, et al. Among authors: wang l. J Med Chem. 2022 Jan 27;65(2):1352-1369. doi: 10.1021/acs.jmedchem.1c00804. Epub 2021 Nov 22. J Med Chem. 2022. PMID: 34807584 Free PMC article.

8

Nanomedicines with high drug availability and drug sensitivity overcome hypoxia-associated drug resistance.

Liu Y, Dong W, Ma Y, Dou J, Jiang W, Wang L, Wang Q, Li S, Wang Y, Li M. Liu Y, et al. Among authors: wang l, wang y, wang q. Biomaterials. 2023 Mar;294:122023. doi: 10.1016/j.biomaterials.2023.122023. Epub 2023 Jan 22. Biomaterials. 2023. PMID: 36708621

9

Comparative genomics analysis and transposon mutagenesis provides new insights into high menaquinone-7 biosynthetic potential of Bacillus subtilis natto.

Jiang C, Zhao G, Wang H, Zheng W, Zhang R, Wang L, Zheng Z. Jiang C, et al. Among authors: wang h, wang l. Gene. 2024 May 20;907:148264. doi: 10.1016/j.gene.2024.148264. Epub 2024 Feb 10. Gene. 2024. PMID: 38346457

10

mTORC1-mediated downregulation of COX2 restrains tumor growth caused by TSC2 deficiency.

Li H, Jin F, Jiang K, Ji S, Wang L, Ni Z, Chen X, Hu Z, Zhang H, Liu Y, Qin Y, Zha X. Li H, et al. Among authors: wang l. Oncotarget. 2016 May 10;7(19):28435-47. doi: 10.18632/oncotarget.8633. Oncotarget. 2016. PMID: 27078846 Free PMC article.

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