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5,347 results

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The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs.
Liu PY, Sokolowski N, Guo ST, Siddiqi F, Atmadibrata B, Telfer TJ, Sun Y, Zhang L, Yu D, Mccarroll J, Liu B, Yang RH, Guo XY, Tee AE, Itoh K, Wang J, Kavallaris M, Haber M, Norris MD, Cheung BB, Byrne JA, Ziegler DS, Marshall GM, Dinger ME, Codd R, Zhang XD, Liu T. Liu PY, et al. Oncotarget. 2016 Nov 29;7(48):79217-79232. doi: 10.18632/oncotarget.12640. Oncotarget. 2016. PMID: 27764794 Free PMC article.
JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis.
Lynch JR, Salik B, Connerty P, Vick B, Leung H, Pijning A, Jeremias I, Spiekermann K, Trahair T, Liu T, Haber M, Norris MD, Woo AJ, Hogg P, Wang J, Wang JY. Lynch JR, et al. Among authors: wang jy, wang j. Leukemia. 2019 Jun;33(6):1400-1410. doi: 10.1038/s41375-018-0354-z. Epub 2019 Jan 8. Leukemia. 2019. PMID: 30622285
JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma.
Wong M, Sun Y, Xi Z, Milazzo G, Poulos RC, Bartenhagen C, Bell JL, Mayoh C, Ho N, Tee AE, Chen X, Li Y, Ciaccio R, Liu PY, Jiang CC, Lan Q, Jayatilleke N, Cheung BB, Haber M, Norris MD, Zhang XD, Marshall GM, Wang JY, Hüttelmaier S, Fischer M, Wong JWH, Xu H, Perini G, Dong Q, George RE, Liu T. Wong M, et al. Among authors: wang jy. Nat Commun. 2019 Jul 25;10(1):3319. doi: 10.1038/s41467-019-11132-w. Nat Commun. 2019. PMID: 31346162 Free PMC article.
The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35.
Liu PY, Tee AE, Milazzo G, Hannan KM, Maag J, Mondal S, Atmadibrata B, Bartonicek N, Peng H, Ho N, Mayoh C, Ciaccio R, Sun Y, Henderson MJ, Gao J, Everaert C, Hulme AJ, Wong M, Lan Q, Cheung BB, Shi L, Wang JY, Simon T, Fischer M, Zhang XD, Marshall GM, Norris MD, Haber M, Vandesompele J, Li J, Mestdagh P, Hannan RD, Dinger ME, Perini G, Liu T. Liu PY, et al. Among authors: wang jy. Nat Commun. 2019 Nov 5;10(1):5026. doi: 10.1038/s41467-019-12971-3. Nat Commun. 2019. PMID: 31690716 Free PMC article.
Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia.
Salik B, Yi H, Hassan N, Santiappillai N, Vick B, Connerty P, Duly A, Trahair T, Woo AJ, Beck D, Liu T, Spiekermann K, Jeremias I, Wang J, Kavallaris M, Haber M, Norris MD, Liebermann DA, D'Andrea RJ, Murriel C, Wang JY. Salik B, et al. Among authors: wang jy, wang j. Cancer Cell. 2020 Aug 10;38(2):263-278.e6. doi: 10.1016/j.ccell.2020.05.014. Epub 2020 Jun 18. Cancer Cell. 2020. PMID: 32559496 Free article.
Targeted Therapy of TERT-Rearranged Neuroblastoma with BET Bromodomain Inhibitor and Proteasome Inhibitor Combination Therapy.
Chen J, Nelson C, Wong M, Tee AE, Liu PY, La T, Fletcher JI, Kamili A, Mayoh C, Bartenhagen C, Trahair TN, Xu N, Jayatilleke N, Wong M, Peng H, Atmadibrata B, Cheung BB, Lan Q, Bryan TM, Mestdagh P, Vandesompele J, Combaret V, Boeva V, Wang JY, Janoueix-Lerosey I, Cowley MJ, MacKenzie KL, Dolnikov A, Li J, Polly P, Marshall GM, Reddel RR, Norris MD, Haber M, Fischer M, Zhang XD, Pickett HA, Liu T. Chen J, et al. Among authors: wang jy. Clin Cancer Res. 2021 Mar 1;27(5):1438-1451. doi: 10.1158/1078-0432.CCR-20-3044. Epub 2020 Dec 11. Clin Cancer Res. 2021. PMID: 33310889
The pan-cancer lncRNA PLANE regulates an alternative splicing program to promote cancer pathogenesis.
Teng L, Feng YC, Guo ST, Wang PL, Qi TF, Yue YM, Wang SX, Zhang SN, Tang CX, La T, Zhang YY, Zhao XH, Gao JN, Wei LY, Zhang D, Wang JY, Shi Y, Liu XY, Li JM, Cao H, Liu T, Thorne RF, Jin L, Shao FM, Zhang XD. Teng L, et al. Among authors: wang pl, wang jy, wang sx. Nat Commun. 2021 Jun 18;12(1):3734. doi: 10.1038/s41467-021-24099-4. Nat Commun. 2021. PMID: 34145290 Free PMC article.
5,347 results