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The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs.
Liu PY, Sokolowski N, Guo ST, Siddiqi F, Atmadibrata B, Telfer TJ, Sun Y, Zhang L, Yu D, Mccarroll J, Liu B, Yang RH, Guo XY, Tee AE, Itoh K, Wang J, Kavallaris M, Haber M, Norris MD, Cheung BB, Byrne JA, Ziegler DS, Marshall GM, Dinger ME, Codd R, Zhang XD, Liu T. Liu PY, et al. Oncotarget. 2016 Nov 29;7(48):79217-79232. doi: 10.18632/oncotarget.12640. Oncotarget. 2016. PMID: 27764794 Free PMC article.
JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis.
Lynch JR, Salik B, Connerty P, Vick B, Leung H, Pijning A, Jeremias I, Spiekermann K, Trahair T, Liu T, Haber M, Norris MD, Woo AJ, Hogg P, Wang J, Wang JY. Lynch JR, et al. Among authors: wang jy, wang j. Leukemia. 2019 Jun;33(6):1400-1410. doi: 10.1038/s41375-018-0354-z. Epub 2019 Jan 8. Leukemia. 2019. PMID: 30622285
miR-101 suppresses the development of MLL-rearranged acute myeloid leukemia.
Gonzales-Aloy E, Connerty P, Salik B, Liu B, Woo AJ, Haber M, Norris MD, Wang J, Wang JY. Gonzales-Aloy E, et al. Among authors: wang jy, wang j. Haematologica. 2019 Jul;104(7):e296-e299. doi: 10.3324/haematol.2018.209437. Epub 2019 Feb 21. Haematologica. 2019. PMID: 30792205 Free PMC article. No abstract available.
JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma.
Wong M, Sun Y, Xi Z, Milazzo G, Poulos RC, Bartenhagen C, Bell JL, Mayoh C, Ho N, Tee AE, Chen X, Li Y, Ciaccio R, Liu PY, Jiang CC, Lan Q, Jayatilleke N, Cheung BB, Haber M, Norris MD, Zhang XD, Marshall GM, Wang JY, Hüttelmaier S, Fischer M, Wong JWH, Xu H, Perini G, Dong Q, George RE, Liu T. Wong M, et al. Among authors: wang jy. Nat Commun. 2019 Jul 25;10(1):3319. doi: 10.1038/s41467-019-11132-w. Nat Commun. 2019. PMID: 31346162 Free PMC article.
The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35.
Liu PY, Tee AE, Milazzo G, Hannan KM, Maag J, Mondal S, Atmadibrata B, Bartonicek N, Peng H, Ho N, Mayoh C, Ciaccio R, Sun Y, Henderson MJ, Gao J, Everaert C, Hulme AJ, Wong M, Lan Q, Cheung BB, Shi L, Wang JY, Simon T, Fischer M, Zhang XD, Marshall GM, Norris MD, Haber M, Vandesompele J, Li J, Mestdagh P, Hannan RD, Dinger ME, Perini G, Liu T. Liu PY, et al. Among authors: wang jy. Nat Commun. 2019 Nov 5;10(1):5026. doi: 10.1038/s41467-019-12971-3. Nat Commun. 2019. PMID: 31690716 Free PMC article.
Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia.
Salik B, Yi H, Hassan N, Santiappillai N, Vick B, Connerty P, Duly A, Trahair T, Woo AJ, Beck D, Liu T, Spiekermann K, Jeremias I, Wang J, Kavallaris M, Haber M, Norris MD, Liebermann DA, D'Andrea RJ, Murriel C, Wang JY. Salik B, et al. Among authors: wang jy, wang j. Cancer Cell. 2020 Aug 10;38(2):263-278.e6. doi: 10.1016/j.ccell.2020.05.014. Epub 2020 Jun 18. Cancer Cell. 2020. PMID: 32559496 Free article.
5,351 results