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USP2 inhibition prevents infection with ACE2-dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice.
Dang F, Bai L, Dong J, Hu X, Wang J, Paulo JA, Xiong Y, Liang X, Sun Y, Chen Y, Guo M, Wang X, Huang Z, Inuzuka H, Chen L, Chu C, Liu J, Zhang T, Rezaeian AH, Liu J, Kaniskan HÜ, Zhong B, Zhang J, Letko M, Jin J, Lan K, Wei W. Dang F, et al. Among authors: wang x, wang j. Sci Transl Med. 2023 Dec 6;15(725):eadh7668. doi: 10.1126/scitranslmed.adh7668. Epub 2023 Dec 6. Sci Transl Med. 2023. PMID: 38055802
PRMT1 methylates METTL14 to modulate its oncogenic function.
Wang J, Wang Z, Inuzuka H, Wei W, Liu J. Wang J, et al. Among authors: wang z. Neoplasia. 2023 Aug;42:100912. doi: 10.1016/j.neo.2023.100912. Epub 2023 Jun 1. Neoplasia. 2023. PMID: 37269817 Free PMC article.
Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1.
Zhang T, Xu D, Trefts E, Lv M, Inuzuka H, Song G, Liu M, Lu J, Liu J, Chu C, Wang M, Wang H, Meng H, Liu H, Zhuang Y, Xie X, Dang F, Guan D, Men Y, Jiang S, Jiang C, Dai X, Liu J, Wang Z, Yan P, Wang J, Tu Z, Babuta M, Erickson E, Hillis AL, Dibble CC, Asara JM, Szabo G, Sicinski P, Miao J, Lee YR, Pan L, Shaw RJ, Yuan J, Wei W. Zhang T, et al. Among authors: wang h, wang z, wang j, wang m. Science. 2023 Jun 30;380(6652):1372-1380. doi: 10.1126/science.abn1725. Epub 2023 Jun 29. Science. 2023. PMID: 37384704 Free PMC article.
Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation.
Zhang T, Xu D, Liu J, Wang M, Duan LJ, Liu M, Meng H, Zhuang Y, Wang H, Wang Y, Lv M, Zhang Z, Hu J, Shi L, Guo R, Xie X, Liu H, Erickson E, Wang Y, Yu W, Dang F, Guan D, Jiang C, Dai X, Inuzuka H, Yan P, Wang J, Babuta M, Lian G, Tu Z, Miao J, Szabo G, Fong GH, Karnoub AE, Lee YR, Pan L, Kaelin WG Jr, Yuan J, Wei W. Zhang T, et al. Among authors: wang h, wang j, wang y, wang m. Nat Cell Biol. 2023 Jul;25(7):950-962. doi: 10.1038/s41556-023-01170-4. Epub 2023 Jul 3. Nat Cell Biol. 2023. PMID: 37400498 Free PMC article.
Uncovering Unrecognized Heart Failure With Preserved Ejection Fraction Among Individuals With Obesity and Dyspnea.
Kosyakovsky LB, Liu EE, Wang JK, Myers L, Parekh JK, Knauss H, Lewis GD, Malhotra R, Nayor M, Robbins JM, Gerszten RE, Hamburg NM, McNeill JN, Lau ES, Ho JE. Kosyakovsky LB, et al. Among authors: wang jk. Circ Heart Fail. 2024 May 14:e011366. doi: 10.1161/CIRCHEARTFAILURE.123.011366. Online ahead of print. Circ Heart Fail. 2024. PMID: 38742409
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