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A peptidomimetic modulator of the CaV2.2 N-type calcium channel for chronic pain.
Gomez K, Santiago U, Nelson TS, Allen HN, Calderon-Rivera A, Hestehave S, Rodríguez Palma EJ, Zhou Y, Duran P, Loya-Lopez S, Zhu E, Kumar U, Shields R, Koseli E, McKiver B, Giuvelis D, Zuo W, Inyang KE, Dorame A, Chefdeville A, Ran D, Perez-Miller S, Lu Y, Liu X, Handoko, Arora PS, Patek M, Moutal A, Khanna M, Hu H, Laumet G, King T, Wang J, Damaj MI, Korczeniewska OA, Camacho CJ, Khanna R. Gomez K, et al. Among authors: wang j. Proc Natl Acad Sci U S A. 2023 Nov 21;120(47):e2305215120. doi: 10.1073/pnas.2305215120. Epub 2023 Nov 16. Proc Natl Acad Sci U S A. 2023. PMID: 37972067 Free PMC article.
Calcium sensitive ring-like oligomers formed by synaptotagmin.
Wang J, Bello O, Auclair SM, Wang J, Coleman J, Pincet F, Krishnakumar SS, Sindelar CV, Rothman JE. Wang J, et al. Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13966-71. doi: 10.1073/pnas.1415849111. Epub 2014 Sep 8. Proc Natl Acad Sci U S A. 2014. PMID: 25201968 Free PMC article.
Cooperation and assortativity with dynamic partner updating.
Wang J, Suri S, Watts DJ. Wang J, et al. Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14363-8. doi: 10.1073/pnas.1120867109. Epub 2012 Aug 17. Proc Natl Acad Sci U S A. 2012. PMID: 22904193 Free PMC article.
Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models.
Teuscher KB, Chowdhury S, Meyers KM, Tian J, Sai J, Van Meveren M, South TM, Sensintaffar JL, Rietz TA, Goswami S, Wang J, Grieb BC, Lorey SL, Howard GC, Liu Q, Moore WJ, Stott GM, Tansey WP, Lee T, Fesik SW. Teuscher KB, et al. Among authors: wang j. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2211297120. doi: 10.1073/pnas.2211297120. Epub 2022 Dec 27. Proc Natl Acad Sci U S A. 2023. PMID: 36574664 Free PMC article.
Redox metabolism maintains the leukemogenic capacity and drug resistance of AML cells.
Huang D, Zhang C, Xiao M, Li X, Chen W, Jiang Y, Yuan Y, Zhang Y, Zou Y, Deng L, Wang Y, Sun Y, Dong W, Zhang Z, Xie L, Yu Z, Chen C, Liu L, Wang J, Yang Y, Yang J, Zhao Y, Zheng J. Huang D, et al. Among authors: wang j, wang y. Proc Natl Acad Sci U S A. 2023 Mar 28;120(13):e2210796120. doi: 10.1073/pnas.2210796120. Epub 2023 Mar 22. Proc Natl Acad Sci U S A. 2023. PMID: 36947513 Free PMC article.
Omics analyses of a somatic Trp53R245W/+ breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling.
Yu X, Zhang Y, Xiong S, McDaniel JM, Sun C, Chau GP, Gencel-Augusto J, Chachad D, Morrissey RL, Rao X, Wang J, Lozano G. Yu X, et al. Among authors: wang j. Proc Natl Acad Sci U S A. 2022 Nov 8;119(45):e2210618119. doi: 10.1073/pnas.2210618119. Epub 2022 Nov 2. Proc Natl Acad Sci U S A. 2022. PMID: 36322759 Free PMC article.
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