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IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy.
Zhou T, Damsky W, Weizman OE, McGeary MK, Hartmann KP, Rosen CE, Fischer S, Jackson R, Flavell RA, Wang J, Sanmamed MF, Bosenberg MW, Ring AM. Zhou T, et al. Among authors: wang j. Nature. 2020 Jul;583(7817):609-614. doi: 10.1038/s41586-020-2422-6. Epub 2020 Jun 24. Nature. 2020. PMID: 32581358 Free PMC article.
Changes in serum interleukin-8 (IL-8) levels reflect and predict response to anti-PD-1 treatment in melanoma and non-small-cell lung cancer patients.
Sanmamed MF, Perez-Gracia JL, Schalper KA, Fusco JP, Gonzalez A, Rodriguez-Ruiz ME, Oñate C, Perez G, Alfaro C, Martín-Algarra S, Andueza MP, Gurpide A, Morgado M, Wang J, Bacchiocchi A, Halaban R, Kluger H, Chen L, Sznol M, Melero I. Sanmamed MF, et al. Among authors: wang j. Ann Oncol. 2017 Aug 1;28(8):1988-1995. doi: 10.1093/annonc/mdx190. Ann Oncol. 2017. PMID: 28595336 Free PMC article.
Expression Analysis and Significance of PD-1, LAG-3, and TIM-3 in Human Non-Small Cell Lung Cancer Using Spatially Resolved and Multiparametric Single-Cell Analysis.
Datar I, Sanmamed MF, Wang J, Henick BS, Choi J, Badri T, Dong W, Mani N, Toki M, Mejías LD, Lozano MD, Perez-Gracia JL, Velcheti V, Hellmann MD, Gainor JF, McEachern K, Jenkins D, Syrigos K, Politi K, Gettinger S, Rimm DL, Herbst RS, Melero I, Chen L, Schalper KA. Datar I, et al. Among authors: wang j. Clin Cancer Res. 2019 Aug 1;25(15):4663-4673. doi: 10.1158/1078-0432.CCR-18-4142. Epub 2019 May 3. Clin Cancer Res. 2019. PMID: 31053602 Free PMC article.
The RNA helicase Dhx15 mediates Wnt-induced antimicrobial protein expression in Paneth cells.
Wang Y, He K, Sheng B, Lei X, Tao W, Zhu X, Wei Z, Fu R, Wang A, Bai S, Zhang Z, Hong N, Ye C, Tian Y, Wang J, Li M, Zhang K, Li L, Yang H, Li HB, Flavell RA, Zhu S. Wang Y, et al. Among authors: wang j, wang a. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2017432118. doi: 10.1073/pnas.2017432118. Proc Natl Acad Sci U S A. 2021. PMID: 33483420 Free PMC article.
A Burned-Out CD8+ T-cell Subset Expands in the Tumor Microenvironment and Curbs Cancer Immunotherapy.
Sanmamed MF, Nie X, Desai SS, Villaroel-Espindola F, Badri T, Zhao D, Kim AW, Ji L, Zhang T, Quinlan E, Cheng X, Han X, Vesely MD, Nassar AF, Sun J, Zhang Y, Kim TK, Wang J, Melero I, Herbst RS, Schalper KA, Chen L. Sanmamed MF, et al. Among authors: wang j. Cancer Discov. 2021 Jul;11(7):1700-1715. doi: 10.1158/2159-8290.CD-20-0962. Epub 2021 Mar 3. Cancer Discov. 2021. PMID: 33658301 Free PMC article.
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