Wang H - Search Results

1

Allosterically inhibited PFKL via prostaglandin E2 withholds glucose metabolism and ovarian cancer invasiveness.

Chen S, Wu Y, Gao Y, Wu C, Wang Y, Hou C, Ren M, Zhang S, Zhu Q, Zhang J, Yao Y, Huang M, Qi YB, Liu XS, Horng T, Wang H, Ye D, Zhu Z, Zhao S, Fan G. Chen S, et al. Among authors: wang h, wang y. Cell Rep. 2023 Oct 31;42(10):113246. doi: 10.1016/j.celrep.2023.113246. Epub 2023 Oct 12. Cell Rep. 2023. PMID: 37831605 Free article.

2

Key elements for designing and performing a CRISPR/Cas9-based genetic screen.

Shang W, Wang F, Fan G, Wang H. Shang W, et al. Among authors: wang h, wang f. J Genet Genomics. 2017 Sep 20;44(9):439-449. doi: 10.1016/j.jgg.2017.09.005. Epub 2017 Sep 22. J Genet Genomics. 2017. PMID: 28967615 Review.

3

Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation.

Shang W, Jiang Y, Boettcher M, Ding K, Mollenauer M, Liu Z, Wen X, Liu C, Hao P, Zhao S, McManus MT, Wei L, Weiss A, Wang H. Shang W, et al. Among authors: wang h. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4051-E4060. doi: 10.1073/pnas.1801340115. Epub 2018 Apr 9. Proc Natl Acad Sci U S A. 2018. PMID: 29632189 Free PMC article.

4

CRISPR/Cas9-Based Genetic Screening to Study T-Cell Function.

Shang W, Wang F, Zhu Q, Wang L, Wang H. Shang W, et al. Among authors: wang h, wang f, wang l. Methods Mol Biol. 2020;2111:59-70. doi: 10.1007/978-1-0716-0266-9_5. Methods Mol Biol. 2020. PMID: 31933198

5

Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy.

Li W, Qiu S, Chen J, Jiang S, Chen W, Jiang J, Wang F, Si W, Shu Y, Wei P, Fan G, Tian R, Wu H, Xu C, Wang H. Li W, et al. Among authors: wang h, wang f. Immunity. 2020 Aug 18;53(2):456-470.e6. doi: 10.1016/j.immuni.2020.07.011. Epub 2020 Aug 5. Immunity. 2020. PMID: 32758419 Free article.

6

NAD⁺ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells.

Wang Y, Wang F, Wang L, Qiu S, Yao Y, Yan C, Xiong X, Chen X, Ji Q, Cao J, Gao G, Li D, Zhang L, Guo Z, Wang R, Wang H, Fan G. Wang Y, et al. Among authors: wang h, wang f, wang l, wang r. Cell Rep. 2021 Aug 10;36(6):109516. doi: 10.1016/j.celrep.2021.109516. Cell Rep. 2021. PMID: 34380043 Free article.

7

A core epitope targeting antibody of SARS-CoV-2.

Zhao S, Liu F, Qiu S, Lan Q, Wu Y, Xu W, Ke J, Yang J, Liu X, Wang K, Guo H, Xia S, Zhang F, Wang J, Hu X, Lu L, Jiang S, Zhao S, Liu L, Xie Y, Yang X, Wang H, Zhong G. Zhao S, et al. Among authors: wang h, wang k, wang j. Protein Cell. 2022 Oct 26;14(1):74-78. doi: 10.1093/procel/pwac042. eCollection 2023 Jan. Protein Cell. 2022. PMID: 36726762 Free PMC article. No abstract available.

8

Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness.

Chen J, Qiu S, Li W, Wang K, Zhang Y, Yang H, Liu B, Li G, Li L, Chen M, Lan J, Niu J, He P, Cheng L, Fan G, Liu X, Song X, Xu C, Wu H, Wang H. Chen J, et al. Among authors: wang h, wang k. Cell Res. 2023 May;33(5):341-354. doi: 10.1038/s41422-023-00789-0. Epub 2023 Mar 8. Cell Res. 2023. PMID: 36882513 Free PMC article.

9

Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity.

Yan C, Zheng L, Jiang S, Yang H, Guo J, Jiang LY, Li T, Zhang H, Bai Y, Lou Y, Zhang Q, Liang T, Schamel W, Wang H, Yang W, Wang G, Zhu ZJ, Song BL, Xu C. Yan C, et al. Among authors: wang h, wang g. Cancer Cell. 2023 Jul 10;41(7):1276-1293.e11. doi: 10.1016/j.ccell.2023.04.016. Epub 2023 May 26. Cancer Cell. 2023. PMID: 37244259

10

THEMIS is a substrate and allosteric activator of SHP1, playing dual roles during T cell development.

Zhang J, Jiang Z, Zhang X, Yang Z, Wang J, Chen J, Chen L, Song M, Zhang Y, Huang M, Chen S, Xiong X, Wang Y, Hao P, Horng T, Zhuang M, Zhang L, Zuo E, Bai F, Zheng J, Wang H, Fan G. Zhang J, et al. Among authors: wang h, wang j, wang y. Nat Struct Mol Biol. 2024 Jan;31(1):54-67. doi: 10.1038/s41594-023-01131-3. Epub 2024 Jan 4. Nat Struct Mol Biol. 2024. PMID: 38177672

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