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SIRT1 in forebrain excitatory neurons produces sexually dimorphic effects on depression-related behaviors and modulates neuronal excitability and synaptic transmission in the medial prefrontal cortex.
Lei Y, Wang J, Wang D, Li C, Liu B, Fang X, You J, Guo M, Lu XY. Lei Y, et al. Among authors: wang j, wang d. Mol Psychiatry. 2020 May;25(5):1094-1111. doi: 10.1038/s41380-019-0352-1. Epub 2019 Jan 31. Mol Psychiatry. 2020. PMID: 30705425 Free PMC article.
Reactivating a positive feedback loop VTA-BLA-NAc circuit associated with positive experience ameliorates the attenuated reward sensitivity induced by chronic stress.
Sun L, You J, Sun F, Cui M, Wang J, Wang W, Wang D, Liu D, Xu Z, Qiu C, Liu B, Yan H. Sun L, et al. Among authors: wang w, wang j, wang d. Neurobiol Stress. 2021 Jul 24;15:100370. doi: 10.1016/j.ynstr.2021.100370. eCollection 2021 Nov. Neurobiol Stress. 2021. PMID: 34381852 Free PMC article.
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