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SAR1B senses leucine levels to regulate mTORC1 signalling.
Chen J, Ou Y, Luo R, Wang J, Wang D, Guan J, Li Y, Xia P, Chen PR, Liu Y. Chen J, et al. Among authors: wang j, wang d. Nature. 2021 Aug;596(7871):281-284. doi: 10.1038/s41586-021-03768-w. Epub 2021 Jul 21. Nature. 2021. PMID: 34290409
Lung adenocarcinoma-intrinsic GBE1 signaling inhibits anti-tumor immunity.
Li L, Yang L, Cheng S, Fan Z, Shen Z, Xue W, Zheng Y, Li F, Wang D, Zhang K, Lian J, Wang D, Zhu Z, Zhao J, Zhang Y. Li L, et al. Among authors: wang d. Mol Cancer. 2019 Jun 20;18(1):108. doi: 10.1186/s12943-019-1027-x. Mol Cancer. 2019. PMID: 31221150 Free PMC article.
Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells.
Wang F, Wang Q, Zhou ZW, Yu SN, Pan ST, He ZX, Zhang X, Wang D, Yang YX, Yang T, Sun T, Li M, Qiu JX, Zhou SF. Wang F, et al. Among authors: wang d, wang q. Drug Des Devel Ther. 2015 Jan 17;9:537-60. doi: 10.2147/DDDT.S73689. eCollection 2015. Drug Des Devel Ther. 2015. PMID: 25632222 Free PMC article.
Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and NCI-N78 cells.
Yuan CX, Zhou ZW, Yang YX, He ZX, Zhang X, Wang D, Yang T, Pan SY, Chen XW, Zhou SF. Yuan CX, et al. Among authors: wang d. Drug Des Devel Ther. 2015 Mar 2;9:1293-318. doi: 10.2147/DDDT.S74964. eCollection 2015. Drug Des Devel Ther. 2015. PMID: 25767376 Free PMC article.
Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells.
Ding YH, Zhou ZW, Ha CF, Zhang XY, Pan ST, He ZX, Edelman JL, Wang D, Yang YX, Zhang X, Duan W, Yang T, Qiu JX, Zhou SF. Ding YH, et al. Among authors: wang d. Drug Des Devel Ther. 2015 Jan 9;9:425-64. doi: 10.2147/DDDT.S74062. eCollection 2015. Drug Des Devel Ther. 2015. PMID: 25624750 Free PMC article.
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