Wang CH - Search Results

1

Development of a variant of dinutuximab with enhanced antitumor efficacy and reduced induction of neuropathic pain.

Liu XY, Chen YL, Liu GJ, Deng XN, Cui Y, Tan J, Dong XC, Li HY, Chen GJ, Ou ZM, Wang CH. Liu XY, et al. Among authors: wang ch. FEBS Open Bio. 2022 Sep;12(9):1644-1656. doi: 10.1002/2211-5463.13464. Epub 2022 Aug 18. FEBS Open Bio. 2022. PMID: 35792784 Free PMC article.

2

Analgesic effects of nerve growth factor-directed monoclonal antibody on diabetic neuralgia in an animal model.

Dong X, Li H, Pei M, Tan J, Chen G, Li S, Xie Z, Wang Q, Wang G, Chen YL, Wang C. Dong X, et al. FEBS Open Bio. 2022 Jul;12(7):1325-1335. doi: 10.1002/2211-5463.13410. Epub 2022 May 3. FEBS Open Bio. 2022. PMID: 35417079 Free PMC article.

3

A bispecific antibody targeting HER2 and PD-L1 inhibits tumor growth with superior efficacy.

Chen YL, Cui Y, Liu X, Liu G, Dong X, Tang L, Hung Y, Wang C, Feng MQ. Chen YL, et al. J Biol Chem. 2021 Dec;297(6):101420. doi: 10.1016/j.jbc.2021.101420. Epub 2021 Nov 16. J Biol Chem. 2021. PMID: 34798072 Free PMC article.

4

NGF monoclonal antibody DS002 alleviates chemotherapy-induced peripheral neuropathy in rats.

Liang ZJ, Tan J, Tang L, Xie ZB, Chen GJ, Liu GJ, Yuan L, Wang KX, Ding HP, Qiu H, Wang Q, Wang GF, Chen YL, Wang CH. Liang ZJ, et al. Among authors: wang kx, wang gf, wang ch, wang q. Acta Pharmacol Sin. 2022 Nov;43(11):2841-2847. doi: 10.1038/s41401-022-00904-8. Epub 2022 Apr 25. Acta Pharmacol Sin. 2022. PMID: 35468993 Free PMC article.

5

ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker.

Chen Y, Zhang YN, Yan R, Wang G, Zhang Y, Zhang ZR, Li Y, Ou J, Chu W, Liang Z, Wang Y, Chen YL, Chen G, Wang Q, Zhou Q, Zhang B, Wang C. Chen Y, et al. Signal Transduct Target Ther. 2021 Aug 25;6(1):315. doi: 10.1038/s41392-021-00740-y. Signal Transduct Target Ther. 2021. PMID: 34433803 Free PMC article.

6

Tyrphostin A9 protects axons in experimental autoimmune encephalomyelitis through activation of ERKs.

Dai X, Wang Y, Li Y, Zhong Y, Pei M, Long J, Dong X, Chen YL, Wang Q, Wang G, Gold BG, Vandenbark AA, Neve KA, Offner H, Wang C. Dai X, et al. Life Sci. 2022 Apr 1;294:120383. doi: 10.1016/j.lfs.2022.120383. Epub 2022 Feb 7. Life Sci. 2022. PMID: 35143827 Free PMC article.

7

HER2/PD1 bispecific antibody in IgG4 subclass with superior anti-tumour activities.

Chu W, Xu H, Wang Y, Xie Y, Chen YL, Tan X, Huang C, Wang G, Wang Q, Luo W, Xia N, Geng M, Xie Z, Wang C. Chu W, et al. Clin Transl Med. 2022 Apr;12(4):e791. doi: 10.1002/ctm2.791. Clin Transl Med. 2022. PMID: 35384333 Free PMC article. No abstract available.

8

PD-L1/TIGIT bispecific antibody showed survival advantage in animal model.

Mu S, Liang Z, Wang Y, Chu W, Chen YL, Wang Q, Wang G, Wang C. Mu S, et al. Clin Transl Med. 2022 May;12(5):e754. doi: 10.1002/ctm2.754. Clin Transl Med. 2022. PMID: 35522941 Free PMC article. No abstract available.

9

Enzyme-linked immunosorbent assays for quantification of MMAE-conjugated ADCs and total antibodies in cynomolgus monkey sera.

Pei M, Liu T, Ouyang L, Sun J, Deng X, Sun X, Wu W, Huang P, Chen YL, Tan X, Liu X, Zhu P, Liu Y, Wang D, Wu J, Wang Q, Wang G, Gong L, Qin Q, Wang C. Pei M, et al. J Pharm Anal. 2022 Aug;12(4):645-652. doi: 10.1016/j.jpha.2021.11.005. Epub 2021 Nov 24. J Pharm Anal. 2022. PMID: 36105165 Free PMC article.

10

Construction of paclitaxel-based antibody-drug conjugates with a PEGylated linker to achieve superior therapeutic index.

Shao T, Chen T, Chen Y, Liu X, Chen YL, Wang Q, Zhu T, Guo M, Li H, Ju D, Wang C. Shao T, et al. Signal Transduct Target Ther. 2020 Jul 29;5(1):132. doi: 10.1038/s41392-020-00247-y. Signal Transduct Target Ther. 2020. PMID: 32728048 Free PMC article. No abstract available.

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