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UTX inactivation in germinal center B cells promotes the development of multiple myeloma with extramedullary disease.
Rizq O, Mimura N, Oshima M, Momose S, Takayama N, Itokawa N, Koide S, Shibamiya A, Miyamoto-Nagai Y, Rizk M, Nakajima-Takagi Y, Aoyama K, Wang C, Saraya A, Ito R, Seimiya M, Watanabe M, Yamasaki S, Shibata T, Yamaguchi K, Furukawa Y, Chiba T, Sakaida E, Nakaseko C, Tamaru JI, Tai YT, Anderson KC, Honda H, Iwama A. Rizq O, et al. Among authors: wang c. Leukemia. 2023 Sep;37(9):1895-1907. doi: 10.1038/s41375-023-01928-7. Epub 2023 May 17. Leukemia. 2023. PMID: 37198323 Free PMC article.
Direct activation of STAT5 by ETV6-LYN fusion protein promotes induction of myeloproliferative neoplasm with myelofibrosis.
Takeda Y, Nakaseko C, Tanaka H, Takeuchi M, Yui M, Saraya A, Miyagi S, Wang C, Tanaka S, Ohwada C, Sakaida E, Yamaguchi N, Yokote K, Hennighausen L, Iwama A. Takeda Y, et al. Among authors: wang c. Br J Haematol. 2011 Jun;153(5):589-98. doi: 10.1111/j.1365-2141.2011.08663.x. Epub 2011 Apr 15. Br J Haematol. 2011. PMID: 21492125 Free PMC article.
The TIF1β-HP1 system maintains transcriptional integrity of hematopoietic stem cells.
Miyagi S, Koide S, Saraya A, Wendt GR, Oshima M, Konuma T, Yamazaki S, Mochizuki-Kashio M, Nakajima-Takagi Y, Wang C, Chiba T, Kitabayashi I, Nakauchi H, Iwama A. Miyagi S, et al. Among authors: wang c. Stem Cell Reports. 2014 Jan 23;2(2):145-52. doi: 10.1016/j.stemcr.2013.12.008. eCollection 2014 Feb 11. Stem Cell Reports. 2014. PMID: 24527388 Free PMC article.
Downregulation of rRNA transcription triggers cell differentiation.
Hayashi Y, Kuroda T, Kishimoto H, Wang C, Iwama A, Kimura K. Hayashi Y, et al. Among authors: wang c. PLoS One. 2014 May 30;9(5):e98586. doi: 10.1371/journal.pone.0098586. eCollection 2014. PLoS One. 2014. PMID: 24879416 Free PMC article.
Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation.
Sashida G, Harada H, Matsui H, Oshima M, Yui M, Harada Y, Tanaka S, Mochizuki-Kashio M, Wang C, Saraya A, Muto T, Hayashi Y, Suzuki K, Nakajima H, Inaba T, Koseki H, Huang G, Kitamura T, Iwama A. Sashida G, et al. Among authors: wang c. Nat Commun. 2014 Jun 23;5:4177. doi: 10.1038/ncomms5177. Nat Commun. 2014. PMID: 24953053 Free article.
Histone acetylation mediated by Brd1 is crucial for Cd8 gene activation during early thymocyte development.
Mishima Y, Wang C, Miyagi S, Saraya A, Hosokawa H, Mochizuki-Kashio M, Nakajima-Takagi Y, Koide S, Negishi M, Sashida G, Naito T, Ishikura T, Onodera A, Nakayama T, Tenen DG, Yamaguchi N, Koseki H, Taniuchi I, Iwama A. Mishima Y, et al. Among authors: wang c. Nat Commun. 2014 Dec 18;5:5872. doi: 10.1038/ncomms6872. Nat Commun. 2014. PMID: 25519988 Free PMC article.
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