Wang C - Search Results

1

NLRP3 inflammasome activation triggers gasdermin D-independent inflammation.

Wang C, Yang T, Xiao J, Xu C, Alippe Y, Sun K, Kanneganti TD, Monahan JB, Abu-Amer Y, Lieberman J, Mbalaviele G. Wang C, et al. Sci Immunol. 2021 Oct 22;6(64):eabj3859. doi: 10.1126/sciimmunol.abj3859. Epub 2021 Oct 22. Sci Immunol. 2021. PMID: 34678046 Free PMC article.

2

Poly-ADP-ribosylation-mediated degradation of ARTD1 by the NLRP3 inflammasome is a prerequisite for osteoclast maturation.

Wang C, Qu C, Alippe Y, Bonar SL, Civitelli R, Abu-Amer Y, Hottiger MO, Mbalaviele G. Wang C, et al. Cell Death Dis. 2016 Mar 24;7(3):e2153. doi: 10.1038/cddis.2016.58. Cell Death Dis. 2016. PMID: 27010854 Free PMC article.

3

Chronic inflammation triggered by the NLRP3 inflammasome in myeloid cells promotes growth plate dysplasia by mesenchymal cells.

Wang C, Xu CX, Alippe Y, Qu C, Xiao J, Schipani E, Civitelli R, Abu-Amer Y, Mbalaviele G. Wang C, et al. Sci Rep. 2017 Jul 7;7(1):4880. doi: 10.1038/s41598-017-05033-5. Sci Rep. 2017. PMID: 28687790 Free PMC article.

4

Bone matrix components activate the NLRP3 inflammasome and promote osteoclast differentiation.

Alippe Y, Wang C, Ricci B, Xiao J, Qu C, Zou W, Novack DV, Abu-Amer Y, Civitelli R, Mbalaviele G. Alippe Y, et al. Among authors: wang c. Sci Rep. 2017 Jul 26;7(1):6630. doi: 10.1038/s41598-017-07014-0. Sci Rep. 2017. PMID: 28747793 Free PMC article.

5

Selective inhibition of the p38α MAPK-MK2 axis inhibits inflammatory cues including inflammasome priming signals.

Wang C, Hockerman S, Jacobsen EJ, Alippe Y, Selness SR, Hope HR, Hirsch JL, Mnich SJ, Saabye MJ, Hood WF, Bonar SL, Abu-Amer Y, Haimovich A, Hoffman HM, Monahan JB, Mbalaviele G. Wang C, et al. J Exp Med. 2018 May 7;215(5):1315-1325. doi: 10.1084/jem.20172063. Epub 2018 Mar 16. J Exp Med. 2018. PMID: 29549113 Free PMC article.

6

Inhibition of the Stromal p38MAPK/MK2 Pathway Limits Breast Cancer Metastases and Chemotherapy-Induced Bone Loss.

Murali B, Ren Q, Luo X, Faget DV, Wang C, Johnson RM, Gruosso T, Flanagan KC, Fu Y, Leahy K, Alspach E, Su X, Ross MH, Burnette B, Weilbaecher KN, Park M, Mbalaviele G, Monahan JB, Stewart SA. Murali B, et al. Among authors: wang c. Cancer Res. 2018 Oct 1;78(19):5618-5630. doi: 10.1158/0008-5472.CAN-18-0234. Epub 2018 Aug 9. Cancer Res. 2018. PMID: 30093561 Free PMC article.

7

Gasdermin D mediates the pathogenesis of neonatal-onset multisystem inflammatory disease in mice.

Xiao J, Wang C, Yao JC, Alippe Y, Xu C, Kress D, Civitelli R, Abu-Amer Y, Kanneganti TD, Link DC, Mbalaviele G. Xiao J, et al. Among authors: wang c. PLoS Biol. 2018 Nov 2;16(11):e3000047. doi: 10.1371/journal.pbio.3000047. eCollection 2018 Nov. PLoS Biol. 2018. PMID: 30388107 Free PMC article.

8

Role of APD-Ribosylation in Bone Health and Disease.

Wang C, Mbalaviele G. Wang C, et al. Cells. 2019 Oct 5;8(10):1201. doi: 10.3390/cells8101201. Cells. 2019. PMID: 31590342 Free PMC article. Review.

9

PARP1 Hinders Histone H2B Occupancy at the NFATc1 Promoter to Restrain Osteoclast Differentiation.

Wang C, Xiao J, Nowak K, Gunasekera K, Alippe Y, Speckman S, Yang T, Kress D, Abu-Amer Y, Hottiger MO, Mbalaviele G. Wang C, et al. J Bone Miner Res. 2020 Apr;35(4):776-788. doi: 10.1002/jbmr.3927. Epub 2020 Jan 7. J Bone Miner Res. 2020. PMID: 31793068 Free PMC article.

10

Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells.

Xiao J, Wang C, Yao JC, Alippe Y, Yang T, Kress D, Sun K, Kostecki KL, Monahan JB, Veis DJ, Abu-Amer Y, Link DC, Mbalaviele G. Xiao J, et al. Among authors: wang c. PLoS Biol. 2020 Aug 6;18(8):e3000807. doi: 10.1371/journal.pbio.3000807. eCollection 2020 Aug. PLoS Biol. 2020. PMID: 32760056 Free PMC article.

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