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BRD4 inhibition impairs DNA mismatch repair, induces mismatch repair mutation signatures and creates therapeutic vulnerability to immune checkpoint blockade in MMR-proficient tumors.
Fu Y, Yang B, Cui Y, Hu X, Li X, Lu F, Qin T, Zhang L, Hu Z, Guo E, Fan J, Xiao R, Li W, Qin X, Hu D, Peng W, Liu J, Wang B, Mills GB, Chen G, Sun C. Fu Y, et al. Among authors: wang b. J Immunother Cancer. 2023 Apr;11(4):e006070. doi: 10.1136/jitc-2022-006070. J Immunother Cancer. 2023. PMID: 37072347 Free PMC article.
Deletion of the intracellular domain of coxsackie and adenovirus receptor (CAR) enhances the expression of itself and boosts the efficiency of current adenovirus-mediated gene therapy in ovarian cancer cell lines in vitro.
Wang B, Chen G, Zhou J, Wu P, Luo D, Huang X, Zhu T, Han Z, Xu G, Wang S, Lu Y, Ma D. Wang B, et al. Among authors: wang s. Cancer Lett. 2007 Apr 18;248(2):299-307. doi: 10.1016/j.canlet.2006.08.002. Epub 2006 Dec 12. Cancer Lett. 2007. PMID: 17166654
Inhibition of PC cell-derived growth factor (PCDGF)/granulin-epithelin precursor (GEP) decreased cell proliferation and invasion through downregulation of cyclin D and CDK4 and inactivation of MMP-2.
Liu Y, Xi L, Liao G, Wang W, Tian X, Wang B, Chen G, Han Z, Wu M, Wang S, Zhou J, Xu G, Lu Y, Ma D. Liu Y, et al. Among authors: wang w, wang s, wang b. BMC Cancer. 2007 Jan 29;7:22. doi: 10.1186/1471-2407-7-22. BMC Cancer. 2007. PMID: 17261172 Free PMC article.
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