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A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.
El Zawily A, Vizeacoumar FS, Dahiya R, Banerjee SL, Bhanumathy KK, Elhasasna H, Hanover G, Sharpe JC, Sanchez MG, Greidanus P, Stacey RG, Moon KM, Alexandrov I, Himanen JP, Nikolov DB, Fonge H, White AP, Foster LJ, Wang B, Toosi BM, Bisson N, Mirzabekov TA, Vizeacoumar FJ, Freywald A. El Zawily A, et al. Among authors: wang b. Clin Cancer Res. 2023 Jul 14;29(14):2686-2701. doi: 10.1158/1078-0432.CCR-22-2535. Clin Cancer Res. 2023. PMID: 36976175 Free PMC article.
Ephrin-A1 and the sheddase ADAM12 are upregulated in COVID-19.
Mendoza R, Saha N, Momeni A, Gabutan E, Alawad M, Dehghani A, Diks J, Lin B, Wang D, Alshal M, Fyke W, Wang B, Himanen JP, Premsrirut P, Nikolov DB. Mendoza R, et al. Among authors: wang d, wang b. Heliyon. 2021 Jun;7(6):e07200. doi: 10.1016/j.heliyon.2021.e07200. Epub 2021 May 31. Heliyon. 2021. PMID: 34095559 Free PMC article.
Time-resolved live-cell spectroscopy reveals EphA2 multimeric assembly.
Shi X, Lingerak R, Herting CJ, Ge Y, Kim S, Toth P, Wang W, Brown BP, Meiler J, Sossey-Alaoui K, Buck M, Himanen J, Hambardzumyan D, Nikolov DB, Smith AW, Wang B. Shi X, et al. Among authors: wang w, wang b. Science. 2023 Dec;382(6674):1042-1050. doi: 10.1126/science.adg5314. Epub 2023 Nov 16. Science. 2023. PMID: 37972196
A role of the SAM domain in EphA2 receptor activation.
Shi X, Hapiak V, Zheng J, Muller-Greven J, Bowman D, Lingerak R, Buck M, Wang BC, Smith AW. Shi X, et al. Sci Rep. 2017 Mar 24;7:45084. doi: 10.1038/srep45084. Sci Rep. 2017. PMID: 28338017 Free PMC article.
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