Wan KF - Search Results

1

Interaction of kendomycin and semi-synthetic analogues with the anti-apoptotic protein Bcl-xl.

Janssen CO, Lim S, Lo EP, Wan KF, Yu VC, Lee MA, Ng SB, Everett MJ, Buss AD, Lane DP, Boyce RS. Janssen CO, et al. Among authors: wan kf. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5771-3. doi: 10.1016/j.bmcl.2008.09.071. Epub 2008 Sep 23. Bioorg Med Chem Lett. 2008. PMID: 18845435

2

Structure-activity relationship studies of phenanthridine-based Bcl-XL inhibitors.

Bernardo PH, Wan KF, Sivaraman T, Xu J, Moore FK, Hung AW, Mok HY, Yu VC, Chai CL. Bernardo PH, et al. Among authors: wan kf. J Med Chem. 2008 Nov 13;51(21):6699-710. doi: 10.1021/jm8005433. Epub 2008 Oct 17. J Med Chem. 2008. PMID: 18925736

3

Chelerythrine and sanguinarine dock at distinct sites on BclXL that are not the classic BH3 binding cleft.

Zhang YH, Bhunia A, Wan KF, Lee MC, Chan SL, Yu VC, Mok YK. Zhang YH, et al. Among authors: wan kf. J Mol Biol. 2006 Dec 1;364(3):536-49. doi: 10.1016/j.jmb.2006.09.023. Epub 2006 Sep 14. J Mol Biol. 2006. PMID: 17011577

4

Chelerythrine induces apoptosis through a Bax/Bak-independent mitochondrial mechanism.

Wan KF, Chan SL, Sukumaran SK, Lee MC, Yu VC. Wan KF, et al. J Biol Chem. 2008 Mar 28;283(13):8423-33. doi: 10.1074/jbc.M707687200. Epub 2008 Jan 29. J Biol Chem. 2008. PMID: 18230621 Free PMC article.

5

Differential scanning fluorimetry as secondary screening platform for small molecule inhibitors of Bcl-XL.

Wan KF, Wang S, Brown CJ, Yu VC, Entzeroth M, Lane DP, Lee MA. Wan KF, et al. Cell Cycle. 2009 Dec;8(23):3943-52. doi: 10.4161/cc.8.23.10114. Epub 2009 Dec 17. Cell Cycle. 2009. PMID: 19901550

6

TRIM39 is a MOAP-1-binding protein that stabilizes MOAP-1 through inhibition of its poly-ubiquitination process.

Lee SS, Fu NY, Sukumaran SK, Wan KF, Wan Q, Yu VC. Lee SS, et al. Among authors: wan kf, wan q. Exp Cell Res. 2009 Apr 15;315(7):1313-25. doi: 10.1016/j.yexcr.2008.11.021. Epub 2008 Dec 9. Exp Cell Res. 2009. PMID: 19100260

7

Structural insights into the design of small molecule inhibitors that selectively antagonize Mcl-1.

Bernardo PH, Sivaraman T, Wan KF, Xu J, Krishnamoorthy J, Song CM, Tian L, Chin JS, Lim DS, Mok HY, Yu VC, Tong JC, Chai CL. Bernardo PH, et al. Among authors: wan kf. J Med Chem. 2010 Mar 11;53(5):2314-8. doi: 10.1021/jm901469p. J Med Chem. 2010. PMID: 20158203

8

A soluble form of the pilus protein FimA targets the VDAC-hexokinase complex at mitochondria to suppress host cell apoptosis.

Sukumaran SK, Fu NY, Tin CB, Wan KF, Lee SS, Yu VC. Sukumaran SK, et al. Among authors: wan kf. Mol Cell. 2010 Mar 26;37(6):768-83. doi: 10.1016/j.molcel.2010.02.015. Mol Cell. 2010. PMID: 20347420 Free article.

9

Discovery of 2-oxopiperazine dengue inhibitors by scaffold morphing of a phenotypic high-throughput screening hit.

Kounde CS, Yeo HQ, Wang QY, Wan KF, Dong H, Karuna R, Dix I, Wagner T, Zou B, Simon O, Bonamy GMC, Yeung BKS, Yokokawa F. Kounde CS, et al. Among authors: wan kf. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1385-1389. doi: 10.1016/j.bmcl.2017.02.005. Epub 2017 Feb 4. Bioorg Med Chem Lett. 2017. PMID: 28216045

10

Identification of covalent active site inhibitors of dengue virus protease.

Koh-Stenta X, Joy J, Wang SF, Kwek PZ, Wee JL, Wan KF, Gayen S, Chen AS, Kang C, Lee MA, Poulsen A, Vasudevan SG, Hill J, Nacro K. Koh-Stenta X, et al. Among authors: wan kf. Drug Des Devel Ther. 2015 Dec 10;9:6389-99. doi: 10.2147/DDDT.S94207. eCollection 2015. Drug Des Devel Ther. 2015. PMID: 26677315 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

28 results

Search Page