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Discovery and multi-parametric optimization of a high-affinity antibody against interleukin-25 with neutralizing activity in a mouse model of skin inflammation.
Bone R, Fennell BJ, Tam A, Sheldon R, Nocka K, Varghese S, Chang CS, Hawerkamp HC, Yeow A, Saunders SP, Hams E, Walsh PT, Cunningham O, Fallon PG. Bone R, et al. Among authors: walsh pt. Antib Ther. 2022 Sep 29;5(4):258-267. doi: 10.1093/abt/tbac022. eCollection 2022 Oct. Antib Ther. 2022. PMID: 36299415 Free PMC article.
IL-36α expression is elevated in ulcerative colitis and promotes colonic inflammation.
Russell SE, Horan RM, Stefanska AM, Carey A, Leon G, Aguilera M, Statovci D, Moran T, Fallon PG, Shanahan F, Brint EK, Melgar S, Hussey S, Walsh PT. Russell SE, et al. Among authors: walsh pt. Mucosal Immunol. 2016 Sep;9(5):1193-204. doi: 10.1038/mi.2015.134. Epub 2016 Jan 27. Mucosal Immunol. 2016. PMID: 26813344 Free article.
74 results