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326 results

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Page 1
Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors.
Barajas JM, Rasouli M, Umeda M, Hiltenbrand R, Abdelhamed S, Mohnani R, Arthur B, Westover T, Thomas ME 3rd, Ashtiani M, Janke LJ, Xu B, Chang TC, Rosikiewicz W, Xiong E, Rolle C, Low J, Krishan R, Song G, Walsh MP, Ma J, Rubnitz JE, Iacobucci I, Chen T, Krippner-Heidenreich A, Zwaan CM, Heidenreich O, Klco JM. Barajas JM, et al. Among authors: walsh mp. Blood. 2024 Feb 15;143(7):619-630. doi: 10.1182/blood.2023021359. Blood. 2024. PMID: 37890156 Free PMC article.
The genomic landscape of core-binding factor acute myeloid leukemias.
Faber ZJ, Chen X, Gedman AL, Boggs K, Cheng J, Ma J, Radtke I, Chao JR, Walsh MP, Song G, Andersson AK, Dang J, Dong L, Liu Y, Huether R, Cai Z, Mulder H, Wu G, Edmonson M, Rusch M, Qu C, Li Y, Vadodaria B, Wang J, Hedlund E, Cao X, Yergeau D, Nakitandwe J, Pounds SB, Shurtleff S, Fulton RS, Fulton LL, Easton J, Parganas E, Pui CH, Rubnitz JE, Ding L, Mardis ER, Wilson RK, Gruber TA, Mullighan CG, Schlenk RF, Paschka P, Döhner K, Döhner H, Bullinger L, Zhang J, Klco JM, Downing JR. Faber ZJ, et al. Among authors: walsh mp. Nat Genet. 2016 Dec;48(12):1551-1556. doi: 10.1038/ng.3709. Epub 2016 Oct 31. Nat Genet. 2016. PMID: 27798625 Free PMC article.
Pediatric non-Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes.
de Rooij JD, Branstetter C, Ma J, Li Y, Walsh MP, Cheng J, Obulkasim A, Dang J, Easton J, Verboon LJ, Mulder HL, Zimmermann M, Koss C, Gupta P, Edmonson M, Rusch M, Lim JY, Reinhardt K, Pigazzi M, Song G, Yeoh AE, Shih LY, Liang DC, Halene S, Krause DS, Zhang J, Downing JR, Locatelli F, Reinhardt D, van den Heuvel-Eibrink MM, Zwaan CM, Fornerod M, Gruber TA. de Rooij JD, et al. Among authors: walsh mp. Nat Genet. 2017 Mar;49(3):451-456. doi: 10.1038/ng.3772. Epub 2017 Jan 23. Nat Genet. 2017. PMID: 28112737 Free PMC article.
AMKL chimeric transcription factors are potent inducers of leukemia.
Dang J, Nance S, Ma J, Cheng J, Walsh MP, Vogel P, Easton J, Song G, Rusch M, Gedman AL, Koss C, Downing JR, Gruber TA. Dang J, et al. Among authors: walsh mp. Leukemia. 2017 Oct;31(10):2228-2234. doi: 10.1038/leu.2017.51. Epub 2017 Feb 8. Leukemia. 2017. PMID: 28174417 Free PMC article.
Germline SAMD9 mutation in siblings with monosomy 7 and myelodysplastic syndrome.
Schwartz JR, Wang S, Ma J, Lamprecht T, Walsh M, Song G, Raimondi SC, Wu G, Walsh MF, McGee RB, Kesserwan C, Nichols KE, Cauff BE, Ribeiro RC, Wlodarski M, Klco JM. Schwartz JR, et al. Leukemia. 2017 Aug;31(8):1827-1830. doi: 10.1038/leu.2017.142. Epub 2017 May 10. Leukemia. 2017. PMID: 28487541 Free PMC article. No abstract available.
De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia.
Hyrenius-Wittsten A, Pilheden M, Sturesson H, Hansson J, Walsh MP, Song G, Kazi JU, Liu J, Ramakrishan R, Garcia-Ruiz C, Nance S, Gupta P, Zhang J, Rönnstrand L, Hultquist A, Downing JR, Lindkvist-Petersson K, Paulsson K, Järås M, Gruber TA, Ma J, Hagström-Andersson AK. Hyrenius-Wittsten A, et al. Among authors: walsh mp. Nat Commun. 2018 May 2;9(1):1770. doi: 10.1038/s41467-018-04180-1. Nat Commun. 2018. PMID: 29720585 Free PMC article.
Clonal dynamics of donor-derived myelodysplastic syndrome after unrelated hematopoietic cell transplantation for high-risk pediatric B-lymphoblastic leukemia.
Schwartz JR, Walsh MP, Ma J, Lamprecht T, Wang S, Wu G, Raimondi S, Triplett BM, Klco JM. Schwartz JR, et al. Among authors: walsh mp. Cold Spring Harb Mol Case Stud. 2018 Oct 1;4(5):a002980. doi: 10.1101/mcs.a002980. Print 2018 Oct. Cold Spring Harb Mol Case Stud. 2018. PMID: 29891567 Free PMC article.
The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms.
Schwartz JR, Ma J, Kamens J, Westover T, Walsh MP, Brady SW, Robert Michael J, Chen X, Montefiori L, Song G, Wu G, Wu H, Branstetter C, Hiltenbrand R, Walsh MF, Nichols KE, Maciaszek JL, Liu Y, Kumar P, Easton J, Newman S, Rubnitz JE, Mullighan CG, Pounds S, Zhang J, Gruber T, Ma X, Klco JM. Schwartz JR, et al. Among authors: walsh mp, walsh mf. Nat Commun. 2021 Feb 12;12(1):985. doi: 10.1038/s41467-021-21255-8. Nat Commun. 2021. PMID: 33579957 Free PMC article.
Integrative Genomic Analysis of Pediatric Myeloid-Related Acute Leukemias Identifies Novel Subtypes and Prognostic Indicators.
Fornerod M, Ma J, Noort S, Liu Y, Walsh MP, Shi L, Nance S, Liu Y, Wang Y, Song G, Lamprecht T, Easton J, Mulder HL, Yergeau D, Myers J, Kamens JL, Obeng EA, Pigazzi M, Jarosova M, Kelaidi C, Polychronopoulou S, Lamba JK, Baker SD, Rubnitz JE, Reinhardt D, van den Heuvel-Eibrink MM, Locatelli F, Hasle H, Klco JM, Downing JR, Zhang J, Pounds S, Zwaan CM, Gruber TA; Berlin-Frankfurt-Munster Study Group (BFM); Dutch Children's Oncology Group (DCOG); Associazione Italiana di Ematologia e Oncologia Pediatrica (AIEOP); Nordic Society for Pediatric Hematology and Oncology (NOPHO); Dutch Children's Oncology Group (DCOG); for St. Jude Children's Research Hospital Study Group (SJCRH). Fornerod M, et al. Among authors: walsh mp. Blood Cancer Discov. 2021 Sep 9;2(6):586-599. doi: 10.1158/2643-3230.BCD-21-0049. eCollection 2021 Nov. Blood Cancer Discov. 2021. PMID: 34778799 Free PMC article.
Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia.
Umeda M, Ma J, Huang BJ, Hagiwara K, Westover T, Abdelhamed S, Barajas JM, Thomas ME, Walsh MP, Song G, Tian L, Liu Y, Chen X, Kolekar P, Tran Q, Foy SG, Maciaszek JL, Kleist AB, Leonti AR, Ju B, Easton J, Wu H, Valentine V, Valentine MB, Liu YC, Ries RE, Smith JL, Parganas E, Iacobucci I, Hiltenbrand R, Miller J, Myers JR, Rampersaud E, Rahbarinia D, Rusch M, Wu G, Inaba H, Wang YC, Alonzo TA, Downing JR, Mullighan CG, Pounds S, Babu MM, Zhang J, Rubnitz JE, Meshinchi S, Ma X, Klco JM. Umeda M, et al. Among authors: walsh mp. Blood Cancer Discov. 2022 May 5;3(3):194-207. doi: 10.1158/2643-3230.BCD-21-0160. Blood Cancer Discov. 2022. PMID: 35176137 Free PMC article.
326 results