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Application of in situ diffraction in high-throughput structure determination platforms.
Aller P, Sanchez-Weatherby J, Foadi J, Winter G, Lobley CM, Axford D, Ashton AW, Bellini D, Brandao-Neto J, Culurgioni S, Douangamath A, Duman R, Evans G, Fisher S, Flaig R, Hall DR, Lukacik P, Mazzorana M, McAuley KE, Mykhaylyk V, Owen RL, Paterson NG, Romano P, Sandy J, Sorensen T, von Delft F, Wagner A, Warren A, Williams M, Stuart DI, Walsh MA. Aller P, et al. Among authors: walsh ma. Methods Mol Biol. 2015;1261:233-53. doi: 10.1007/978-1-4939-2230-7_13. Methods Mol Biol. 2015. PMID: 25502203 Review.
An automatic pipeline for the design of irreversible derivatives identifies a potent SARS-CoV-2 Mpro inhibitor.
Zaidman D, Gehrtz P, Filep M, Fearon D, Gabizon R, Douangamath A, Prilusky J, Duberstein S, Cohen G, Owen CD, Resnick E, Strain-Damerell C, Lukacik P; Covid-Moonshot Consortium; Barr H, Walsh MA, von Delft F, London N. Zaidman D, et al. Among authors: walsh ma. Cell Chem Biol. 2021 Dec 16;28(12):1795-1806.e5. doi: 10.1016/j.chembiol.2021.05.018. Epub 2021 Jun 25. Cell Chem Biol. 2021. PMID: 34174194 Free PMC article.
Sedentary behavior in mice induces metabolic inflexibility by suppressing skeletal muscle pyruvate metabolism.
Siripoksup P, Cao G, Cluntun AA, Maschek JA, Pearce Q, Lang MJ, Jeong MY, Eshima H, Ferrara PJ, Opurum PC, Mahmassani ZS, Peterlin AD, Watanabe S, Walsh MA, Taylor EB, Cox JE, Drummond MJ, Rutter J, Funai K. Siripoksup P, et al. Among authors: walsh ma. J Clin Invest. 2024 Apr 23:e167371. doi: 10.1172/JCI167371. Online ahead of print. J Clin Invest. 2024. PMID: 38652544 Free article.
204 results