Walsh DM - Search Results

1

A vicious cycle of β amyloid-dependent neuronal hyperactivation.

Zott B, Simon MM, Hong W, Unger F, Chen-Engerer HJ, Frosch MP, Sakmann B, Walsh DM, Konnerth A. Zott B, et al. Among authors: walsh dm. Science. 2019 Aug 9;365(6453):559-565. doi: 10.1126/science.aay0198. Science. 2019. PMID: 31395777 Free PMC article.

2

The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease.

Sharon R, Bar-Joseph I, Frosch MP, Walsh DM, Hamilton JA, Selkoe DJ. Sharon R, et al. Among authors: walsh dm. Neuron. 2003 Feb 20;37(4):583-95. doi: 10.1016/s0896-6273(03)00024-2. Neuron. 2003. PMID: 12597857 Free article.

3

Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death.

Leissring MA, Farris W, Chang AY, Walsh DM, Wu X, Sun X, Frosch MP, Selkoe DJ. Leissring MA, et al. Among authors: walsh dm. Neuron. 2003 Dec 18;40(6):1087-93. doi: 10.1016/s0896-6273(03)00787-6. Neuron. 2003. PMID: 14687544 Free article.

4

Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers.

Townsend M, Shankar GM, Mehta T, Walsh DM, Selkoe DJ. Townsend M, et al. Among authors: walsh dm. J Physiol. 2006 Apr 15;572(Pt 2):477-92. doi: 10.1113/jphysiol.2005.103754. Epub 2006 Feb 9. J Physiol. 2006. PMID: 16469784 Free PMC article.

5

Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host.

Meyer-Luehmann M, Coomaraswamy J, Bolmont T, Kaeser S, Schaefer C, Kilger E, Neuenschwander A, Abramowski D, Frey P, Jaton AL, Vigouret JM, Paganetti P, Walsh DM, Mathews PM, Ghiso J, Staufenbiel M, Walker LC, Jucker M. Meyer-Luehmann M, et al. Among authors: walsh dm. Science. 2006 Sep 22;313(5794):1781-4. doi: 10.1126/science.1131864. Science. 2006. PMID: 16990547

6

Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway.

Shankar GM, Bloodgood BL, Townsend M, Walsh DM, Selkoe DJ, Sabatini BL. Shankar GM, et al. Among authors: walsh dm. J Neurosci. 2007 Mar 14;27(11):2866-75. doi: 10.1523/JNEUROSCI.4970-06.2007. J Neurosci. 2007. PMID: 17360908 Free PMC article.

7

Loss of neprilysin function promotes amyloid plaque formation and causes cerebral amyloid angiopathy.

Farris W, Schütz SG, Cirrito JR, Shankar GM, Sun X, George A, Leissring MA, Walsh DM, Qiu WQ, Holtzman DM, Selkoe DJ. Farris W, et al. Among authors: walsh dm. Am J Pathol. 2007 Jul;171(1):241-51. doi: 10.2353/ajpath.2007.070105. Am J Pathol. 2007. PMID: 17591969 Free PMC article.

8

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.

Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ. Shankar GM, et al. Among authors: walsh dm. Nat Med. 2008 Aug;14(8):837-42. doi: 10.1038/nm1782. Epub 2008 Jun 22. Nat Med. 2008. PMID: 18568035 Free PMC article.

9

Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake.

Li S, Hong S, Shepardson NE, Walsh DM, Shankar GM, Selkoe D. Li S, et al. Among authors: walsh dm. Neuron. 2009 Jun 25;62(6):788-801. doi: 10.1016/j.neuron.2009.05.012. Neuron. 2009. PMID: 19555648 Free PMC article.

10

Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease.

Kumar S, Rezaei-Ghaleh N, Terwel D, Thal DR, Richard M, Hoch M, Mc Donald JM, Wüllner U, Glebov K, Heneka MT, Walsh DM, Zweckstetter M, Walter J. Kumar S, et al. Among authors: walsh dm. EMBO J. 2011 Jun 1;30(11):2255-65. doi: 10.1038/emboj.2011.138. Epub 2011 Apr 28. EMBO J. 2011. PMID: 21527912 Free PMC article.

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