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Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation.
Mirchandani AS, Jenkins SJ, Bain CC, Sanchez-Garcia MA, Lawson H, Coelho P, Murphy F, Griffith DM, Zhang A, Morrison T, Ly T, Arienti S, Sadiku P, Watts ER, Dickinson RS, Reyes L, Cooper G, Clark S, Lewis D, Kelly V, Spanos C, Musgrave KM, Delaney L, Harper I, Scott J, Parkinson NJ, Rostron AJ, Baillie JK, Clohisey S, Pridans C, Campana L, Lewis PS, Simpson AJ, Dockrell DH, Schwarze J, Hirani N, Ratcliffe PJ, Pugh CW, Kranc K, Forbes SJ, Whyte MKB, Walmsley SR. Mirchandani AS, et al. Among authors: walmsley sr. Nat Immunol. 2022 Jun;23(6):927-939. doi: 10.1038/s41590-022-01216-z. Epub 2022 May 27. Nat Immunol. 2022. PMID: 35624205 Free PMC article.
The role of HIF-1alpha in myeloid cell inflammation.
Walmsley SR, Cadwallader KA, Chilvers ER. Walmsley SR, et al. Trends Immunol. 2005 Aug;26(8):434-9. doi: 10.1016/j.it.2005.06.007. Trends Immunol. 2005. PMID: 15979406 Review.
The HIF/VHL pathway: from oxygen sensing to innate immunity.
Walmsley SR, McGovern NN, Whyte MK, Chilvers ER. Walmsley SR, et al. Am J Respir Cell Mol Biol. 2008 Mar;38(3):251-5. doi: 10.1165/rcmb.2007-0331TR. Epub 2007 Oct 11. Am J Respir Cell Mol Biol. 2008. PMID: 17932373 Review.
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice.
Walmsley SR, Chilvers ER, Thompson AA, Vaughan K, Marriott HM, Parker LC, Shaw G, Parmar S, Schneider M, Sabroe I, Dockrell DH, Milo M, Taylor CT, Johnson RS, Pugh CW, Ratcliffe PJ, Maxwell PH, Carmeliet P, Whyte MK. Walmsley SR, et al. J Clin Invest. 2011 Mar;121(3):1053-63. doi: 10.1172/JCI43273. Epub 2011 Feb 7. J Clin Invest. 2011. PMID: 21317538 Free PMC article.
67 results