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New and emerging technologies for genetic toxicity testing.
Lynch AM, Sasaki JC, Elespuru R, Jacobson-Kram D, Thybaud V, De Boeck M, Aardema MJ, Aubrecht J, Benz RD, Dertinger SD, Douglas GR, White PA, Escobar PA, Fornace A Jr, Honma M, Naven RT, Rusling JF, Schiestl RH, Walmsley RM, Yamamura E, van Benthem J, Kim JH. Lynch AM, et al. Among authors: walmsley rm. Environ Mol Mutagen. 2011 Apr;52(3):205-23. doi: 10.1002/em.20614. Epub 2010 Aug 25. Environ Mol Mutagen. 2011. PMID: 20740635 Review.
Development of an in vitro PIG-A gene mutation assay in human cells.
Rees BJ, Tate M, Lynch AM, Thornton CA, Jenkins GJ, Walmsley RM, Johnson GE. Rees BJ, et al. Among authors: walmsley rm. Mutagenesis. 2017 Mar 1;32(2):283-297. doi: 10.1093/mutage/gew059. Mutagenesis. 2017. PMID: 28057708 Free PMC article.
Flow cytometric 96-well microplate-based in vitro micronucleus assay with human TK6 cells: protocol optimization and transferability assessment.
Bryce SM, Avlasevich SL, Bemis JC, Tate M, Walmsley RM, Saad F, Van Dijck K, De Boeck M, Van Goethem F, Lukamowicz-Rajska M, Elhajouji A, Dertinger SD. Bryce SM, et al. Among authors: walmsley rm. Environ Mol Mutagen. 2013 Apr;54(3):180-94. doi: 10.1002/em.21760. Epub 2013 Feb 27. Environ Mol Mutagen. 2013. PMID: 23447390
Interlaboratory assessment of the GreenScreen HC GADD45a-GFP genotoxicity screening assay: an enabling study for independent validation as an alternative method.
Billinton N, Hastwell PW, Beerens D, Birrell L, Ellis P, Maskell S, Webster TW, Windebank S, Woestenborghs F, Lynch AM, Scott AD, Tweats DJ, van Gompel J, Rees RW, Walmsley RM. Billinton N, et al. Among authors: walmsley rm. Mutat Res. 2008 May 31;653(1-2):23-33. doi: 10.1016/j.mrgentox.2008.02.011. Epub 2008 Mar 27. Mutat Res. 2008. PMID: 18450500
An analysis of results from 305 compounds tested with the yeast RAD54-GFP genotoxicity assay (GreenScreen GC)-including relative predictivity of regulatory tests and rodent carcinogenesis and performance with autofluorescent and coloured compounds.
Knight AW, Billinton N, Cahill PA, Scott A, Harvey JS, Roberts KJ, Tweats DJ, Keenan PO, Walmsley RM. Knight AW, et al. Among authors: walmsley rm. Mutagenesis. 2007 Nov;22(6):409-16. doi: 10.1093/mutage/gem036. Epub 2007 Sep 28. Mutagenesis. 2007. PMID: 17906314
Ames positive boronic acids are not all eukaryotic genotoxins.
Scott H, Walmsley RM. Scott H, et al. Among authors: walmsley rm. Mutat Res Genet Toxicol Environ Mutagen. 2015 Jan 1;777:68-72. doi: 10.1016/j.mrgentox.2014.12.002. Epub 2014 Dec 15. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 25726177
The GreenScreen genotoxicity assay: a screening validation programme.
Cahill PA, Knight AW, Billinton N, Barker MG, Walsh L, Keenan PO, Williams CV, Tweats DJ, Walmsley RM. Cahill PA, et al. Among authors: walmsley rm. Mutagenesis. 2004 Mar;19(2):105-19. doi: 10.1093/mutage/geh015. Mutagenesis. 2004. PMID: 14981157
58 results