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The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection.
Ali YM, Lynch NJ, Haleem KS, Fujita T, Endo Y, Hansen S, Holmskov U, Takahashi K, Stahl GL, Dudler T, Girija UV, Wallis R, Kadioglu A, Stover CM, Andrew PW, Schwaeble WJ. Ali YM, et al. Among authors: wallis r. PLoS Pathog. 2012;8(7):e1002793. doi: 10.1371/journal.ppat.1002793. Epub 2012 Jul 5. PLoS Pathog. 2012. PMID: 22792067 Free PMC article.
Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2.
Yaseen S, Demopulos G, Dudler T, Yabuki M, Wood CL, Cummings WJ, Tjoelker LW, Fujita T, Sacks S, Garred P, Andrew P, Sim RB, Lachmann PJ, Wallis R, Lynch N, Schwaeble WJ. Yaseen S, et al. Among authors: wallis r. FASEB J. 2017 May;31(5):2210-2219. doi: 10.1096/fj.201601306R. Epub 2017 Feb 10. FASEB J. 2017. PMID: 28188176
., Tjoelker, L. W., Fujita, T., Sacks, S., Garred, P., Andrew, P., Sim, R. B., Lachmann, P. J., Wallis, R., Lynch, N., Schwaeble, W. J. ...
., Tjoelker, L. W., Fujita, T., Sacks, S., Garred, P., Andrew, P., Sim, R. B., Lachmann, P. J., Wallis, R., Lynch, N., …
Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation.
Venkatraman Girija U, Gingras AR, Marshall JE, Panchal R, Sheikh MA, Harper JA, Gál P, Schwaeble WJ, Mitchell DA, Moody PC, Wallis R. Venkatraman Girija U, et al. Among authors: wallis r. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13916-20. doi: 10.1073/pnas.1311113110. Epub 2013 Aug 6. Proc Natl Acad Sci U S A. 2013. PMID: 23922389 Free PMC article.
Two Faces of CwlM, an Essential PknB Substrate, in Mycobacterium tuberculosis.
Turapov O, Forti F, Kadhim B, Ghisotti D, Sassine J, Straatman-Iwanowska A, Bottrill AR, Moynihan PJ, Wallis R, Barthe P, Cohen-Gonsaud M, Ajuh P, Vollmer W, Mukamolova GV. Turapov O, et al. Among authors: wallis r. Cell Rep. 2018 Oct 2;25(1):57-67.e5. doi: 10.1016/j.celrep.2018.09.004. Cell Rep. 2018. PMID: 30282038 Free PMC article.
515 results