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Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS.
Hop PJ, Zwamborn RAJ, Hannon E, Shireby GL, Nabais MF, Walker EM, van Rheenen W, van Vugt JJFA, Dekker AM, Westeneng HJ, Tazelaar GHP, van Eijk KR, Moisse M, Baird D, Al Khleifat A, Iacoangeli A, Ticozzi N, Ratti A, Cooper-Knock J, Morrison KE, Shaw PJ, Basak AN, Chiò A, Calvo A, Moglia C, Canosa A, Brunetti M, Grassano M, Gotkine M, Lerner Y, Zabari M, Vourc'h P, Corcia P, Couratier P, Mora Pardina JS, Salas T, Dion P, Ross JP, Henderson RD, Mathers S, McCombe PA, Needham M, Nicholson G, Rowe DB, Pamphlett R, Mather KA, Sachdev PS, Furlong S, Garton FC, Henders AK, Lin T, Ngo ST, Steyn FJ, Wallace L, Williams KL; BIOS Consortium; Brain MEND Consortium; Neto MM, Cauchi RJ, Blair IP, Kiernan MC, Drory V, Povedano M, de Carvalho M, Pinto S, Weber M, Rouleau GA, Silani V, Landers JE, Shaw CE, Andersen PM, McRae AF, van Es MA, Pasterkamp RJ, Wray NR, McLaughlin RL, Hardiman O, Kenna KP, Tsai E, Runz H, Al-Chalabi A, van den Berg LH, Van Damme P, Mill J, Veldink JH. Hop PJ, et al. Among authors: walker em. Sci Transl Med. 2022 Feb 23;14(633):eabj0264. doi: 10.1126/scitranslmed.abj0264. Epub 2022 Feb 23. Sci Transl Med. 2022. PMID: 35196023 Free PMC article.
Cross-reactive probes on Illumina DNA methylation arrays: a large study on ALS shows that a cautionary approach is warranted in interpreting epigenome-wide association studies.
Hop PJ, Zwamborn RAJ, Hannon EJ, Dekker AM, van Eijk KR, Walker EM, Iacoangeli A, Jones AR, Shatunov A, Khleifat AA, Opie-Martin S, Shaw CE, Morrison KE, Shaw PJ, McLaughlin RL, Hardiman O, Al-Chalabi A, Van Den Berg LH, Mill J, Veldink JH. Hop PJ, et al. Among authors: walker em. NAR Genom Bioinform. 2020 Dec 17;2(4):lqaa105. doi: 10.1093/nargab/lqaa105. eCollection 2020 Dec. NAR Genom Bioinform. 2020. PMID: 33554115 Free PMC article.
Assessing the co-variability of DNA methylation across peripheral cells and tissues: Implications for the interpretation of findings in epigenetic epidemiology.
Hannon E, Mansell G, Walker E, Nabais MF, Burrage J, Kepa A, Best-Lane J, Rose A, Heck S, Moffitt TE, Caspi A, Arseneault L, Mill J. Hannon E, et al. PLoS Genet. 2021 Mar 19;17(3):e1009443. doi: 10.1371/journal.pgen.1009443. eCollection 2021 Mar. PLoS Genet. 2021. PMID: 33739972 Free PMC article.
Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons.
Steg LC, Shireby GL, Imm J, Davies JP, Franklin A, Flynn R, Namboori SC, Bhinge A, Jeffries AR, Burrage J, Neilson GWA, Walker EM, Perfect LW, Price J, McAlonan G, Srivastava DP, Bray NJ, Cope EL, Jones KM, Allen ND, Pishva E, Dempster EL, Lunnon K, Mill J, Hannon E. Steg LC, et al. Among authors: walker em. Mol Brain. 2021 Jun 26;14(1):98. doi: 10.1186/s13041-021-00810-w. Mol Brain. 2021. PMID: 34174924 Free PMC article.
Transcriptional Signatures of Tau and Amyloid Neuropathology.
Castanho I, Murray TK, Hannon E, Jeffries A, Walker E, Laing E, Baulf H, Harvey J, Bradshaw L, Randall A, Moore K, O'Neill P, Lunnon K, Collier DA, Ahmed Z, O'Neill MJ, Mill J. Castanho I, et al. Cell Rep. 2020 Feb 11;30(6):2040-2054.e5. doi: 10.1016/j.celrep.2020.01.063. Cell Rep. 2020. PMID: 32049030 Free PMC article.
Are We Missing Acute Toxicities Associated With Hypofractionated Breast Irradiation? A Report From a Large Multicenter Cohort Study.
Beydoun H, Griffith KA, Jagsi R, Burmeister JW, Moran JM, Vicini FA, Hayman JA, Paximadis P, Boike TP, Walker EM, Pierce LJ, Dominello MM; Michigan Radiation Oncology Quality Consortium (MROQC). Beydoun H, et al. Among authors: walker em. Int J Radiat Oncol Biol Phys. 2024 Feb 15:S0360-3016(24)00303-1. doi: 10.1016/j.ijrobp.2024.01.225. Online ahead of print. Int J Radiat Oncol Biol Phys. 2024. PMID: 38364950
A versatile pumpless multi-channel fluidics system for maintenance and real-time functional assessment of tissue and cells.
Kamat V, Grumbine MK, Bao K, Mokate K, Khalil G, Cook D, Clearwater B, Hirst R, Harman J, Boeck M, Fu Z, Smith LEH, Goswami M, Wubben TJ, Walker EM, Zhu J, Soleimanpour SA, Scarlett JM, Robbings BM, Hass D, Hurley JB, Sweet IR. Kamat V, et al. Among authors: walker em. Cell Rep Methods. 2023 Nov 20;3(11):100642. doi: 10.1016/j.crmeth.2023.100642. Epub 2023 Nov 13. Cell Rep Methods. 2023. PMID: 37963464 Free PMC article.
Factors Associated With Cardiac Radiation Dose Reduction After Hypofractionated Radiation Therapy for Localized, Left-Sided Breast Cancer in a Large Statewide Quality Consortium.
Herr DJ, Moncion A, Griffith KA, Marsh R, Grubb M, Bhatt A, Dominello M, Walker EM, Narayana V, Abu-Isa E, Vicini FA, Hayman JA, Pierce LJ; Michigan Radiation Oncology Quality Consortium. Herr DJ, et al. Among authors: walker em. Int J Radiat Oncol Biol Phys. 2024 Mar 1;118(3):632-638. doi: 10.1016/j.ijrobp.2023.09.013. Epub 2023 Oct 3. Int J Radiat Oncol Biol Phys. 2024. PMID: 37797748
242 results