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p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors.
Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson FS, Tepper J, Chen Z, Lovisa S, Svelto M, Amin S, Srinivasan S, Del Poggetto E, Loponte S, Puca F, Dey P, Malouf GG, Su X, Li L, Lopez-Terrada D, Rakheja D, Lazar AJ, Netto GJ, Rao P, Sgambato A, Maitra A, Tripathi DN, Walker CL, Karam JA, Heffernan TP, Viale A, Roberts CWM, Msaouel P, Tannir NM, Draetta GF, Genovese G. Carugo A, et al. Among authors: walker cl. Cancer Cell. 2019 Feb 11;35(2):204-220.e9. doi: 10.1016/j.ccell.2019.01.006. Cancer Cell. 2019. PMID: 30753823 Free PMC article.
A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
Zhang J, Kim J, Alexander A, Cai S, Tripathi DN, Dere R, Tee AR, Tait-Mulder J, Di Nardo A, Han JM, Kwiatkowski E, Dunlop EA, Dodd KM, Folkerth RD, Faust PL, Kastan MB, Sahin M, Walker CL. Zhang J, et al. Among authors: walker cl. Nat Cell Biol. 2013 Oct;15(10):1186-96. doi: 10.1038/ncb2822. Epub 2013 Aug 18. Nat Cell Biol. 2013. PMID: 23955302 Free PMC article.
Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis.
Liu XD, Yao J, Tripathi DN, Ding Z, Xu Y, Sun M, Zhang J, Bai S, German P, Hoang A, Zhou L, Jonasch D, Zhang X, Conti CJ, Efstathiou E, Tannir NM, Eissa NT, Mills GB, Walker CL, Jonasch E. Liu XD, et al. Among authors: walker cl. Oncogene. 2015 May 7;34(19):2450-60. doi: 10.1038/onc.2014.199. Epub 2014 Jul 7. Oncogene. 2015. PMID: 24998849 Free PMC article.
ATM functions at the peroxisome to induce pexophagy in response to ROS.
Zhang J, Tripathi DN, Jing J, Alexander A, Kim J, Powell RT, Dere R, Tait-Mulder J, Lee JH, Paull TT, Pandita RK, Charaka VK, Pandita TK, Kastan MB, Walker CL. Zhang J, et al. Among authors: walker cl. Nat Cell Biol. 2015 Oct;17(10):1259-1269. doi: 10.1038/ncb3230. Epub 2015 Sep 7. Nat Cell Biol. 2015. PMID: 26344566 Free PMC article.
Targeting MET and AXL overcomes resistance to sunitinib therapy in renal cell carcinoma.
Zhou L, Liu XD, Sun M, Zhang X, German P, Bai S, Ding Z, Tannir N, Wood CG, Matin SF, Karam JA, Tamboli P, Sircar K, Rao P, Rankin EB, Laird DA, Hoang AG, Walker CL, Giaccia AJ, Jonasch E. Zhou L, et al. Among authors: walker cl. Oncogene. 2016 May;35(21):2687-97. doi: 10.1038/onc.2015.343. Epub 2015 Sep 14. Oncogene. 2016. PMID: 26364599 Free PMC article.
The peroxisome as a cell signaling organelle.
Tripathi DN, Walker CL. Tripathi DN, et al. Among authors: walker cl. Curr Opin Cell Biol. 2016 Apr;39:109-12. doi: 10.1016/j.ceb.2016.02.017. Epub 2016 Mar 9. Curr Opin Cell Biol. 2016. PMID: 26967755 Free PMC article. Review.
Dual Chromatin and Cytoskeletal Remodeling by SETD2.
Park IY, Powell RT, Tripathi DN, Dere R, Ho TH, Blasius TL, Chiang YC, Davis IJ, Fahey CC, Hacker KE, Verhey KJ, Bedford MT, Jonasch E, Rathmell WK, Walker CL. Park IY, et al. Among authors: walker cl. Cell. 2016 Aug 11;166(4):950-962. doi: 10.1016/j.cell.2016.07.005. Cell. 2016. PMID: 27518565 Free PMC article.
297 results