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Plasma steroid concentrations reflect acute disease severity and normalise during recovery in people hospitalised with COVID-19.
Devine K, Russell CD, Blanco GR, Walker BR, Homer NZM, Denham SG, Simpson JP, Leavy OC, Elneima O, McAuley HJC, Shikotra A, Singapuri A, Sereno M, Saunders RM, Harris VC, Houchen-Wolloff L, Greening NJ, Lone NI, Thorpe M, Greenhalf W, Chalmers JD, Ho LP, Horsley A, Marks M, Raman B, Moore SC, Dunning J, Semple MG, Andrew R, Wain LV, Evans RA, Brightling CE, Kenneth Baillie J, Reynolds RM; ISARIC4C Investigators and PHOSP-COVID Study Collaborative Group. Devine K, et al. Among authors: walker br. Clin Endocrinol (Oxf). 2024 Apr;100(4):317-327. doi: 10.1111/cen.15012. Epub 2024 Jan 17. Clin Endocrinol (Oxf). 2024. PMID: 38229583
Retinal Arteriolar Wall Remodeling in Diabetes Captured With AOSLO.
Sapoznik KA, Gast TJ, Carmichael-Martins A, Walker BR, Warner RL, Burns SA. Sapoznik KA, et al. Among authors: walker br. Transl Vis Sci Technol. 2023 Nov 1;12(11):16. doi: 10.1167/tvst.12.11.16. Transl Vis Sci Technol. 2023. PMID: 37962539 Free PMC article.
Plasma cortisol-linked gene networks in hepatic and adipose tissues implicate corticosteroid-binding globulin in modulating tissue glucocorticoid action and cardiovascular risk.
Bankier S, Wang L, Crawford A, Morgan RA, Ruusalepp A, Andrew R, Björkegren JLM, Walker BR, Michoel T. Bankier S, et al. Among authors: walker br. Front Endocrinol (Lausanne). 2023 Sep 6;14:1186252. doi: 10.3389/fendo.2023.1186252. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37745713 Free PMC article.
Cystatin C is glucocorticoid responsive, directs recruitment of Trem2+ macrophages, and predicts failure of cancer immunotherapy.
Kleeman SO, Thakir TM, Demestichas B, Mourikis N, Loiero D, Ferrer M, Bankier S, Riazat-Kesh YJRA, Lee H, Chantzichristos D, Regan C, Preall J, Sinha S, Rosin N, Yipp B, de Almeida LGN, Biernaskie J, Dufour A, Tober-Lau P, Ruusalepp A, Bjorkegren JLM, Ralser M, Kurth F, Demichev V, Heywood T, Gao Q, Johannsson G, Koelzer VH, Walker BR, Meyer HV, Janowitz T. Kleeman SO, et al. Among authors: walker br. Cell Genom. 2023 Jun 23;3(8):100347. doi: 10.1016/j.xgen.2023.100347. eCollection 2023 Aug 9. Cell Genom. 2023. PMID: 37601967 Free PMC article.
Contribution of local regeneration of glucocorticoids to tissue steroid pools.
Khan S, Livingstone DEW, Zielinska A, Doig CL, Cobice DF, Esteves CL, Man JTY, Homer NZM, Seckl JR, MacKay CL, Webster SP, Lavery GG, Chapman KE, Walker BR, Andrew R. Khan S, et al. Among authors: walker br. J Endocrinol. 2023 Jul 28;258(3):e230034. doi: 10.1530/JOE-23-0034. Print 2023 Sep 1. J Endocrinol. 2023. PMID: 37343234 Free PMC article.
Memory deficits in a juvenile rat model of type 1 diabetes are due to excess 11β-HSD1 activity, which is upregulated by high glucose concentrations rather than insulin deficiency.
Brossaud J, Bosch-Bouju C, Marissal-Arvy N, Campas-Lebecque MN, Helbling JC, Webster SP, Walker BR, Fioramonti X, Ferreira G, Barat P, Corcuff JB, Moisan MP. Brossaud J, et al. Among authors: walker br. Diabetologia. 2023 Sep;66(9):1735-1747. doi: 10.1007/s00125-023-05942-3. Epub 2023 Jun 10. Diabetologia. 2023. PMID: 37300580
551 results