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Evolution-guided engineering of trans-acyltransferase polyketide synthases.
Mabesoone MFJ, Leopold-Messer S, Minas HA, Chepkirui C, Chawengrum P, Reiter S, Meoded RA, Wolf S, Genz F, Magnus N, Piechulla B, Walker AS, Piel J. Mabesoone MFJ, et al. Among authors: walker as. Science. 2024 Mar 22;383(6689):1312-1317. doi: 10.1126/science.adj7621. Epub 2024 Mar 21. Science. 2024. PMID: 38513027
Artificial intelligence for natural product drug discovery.
Mullowney MW, Duncan KR, Elsayed SS, Garg N, van der Hooft JJJ, Martin NI, Meijer D, Terlouw BR, Biermann F, Blin K, Durairaj J, Gorostiola González M, Helfrich EJN, Huber F, Leopold-Messer S, Rajan K, de Rond T, van Santen JA, Sorokina M, Balunas MJ, Beniddir MA, van Bergeijk DA, Carroll LM, Clark CM, Clevert DA, Dejong CA, Du C, Ferrinho S, Grisoni F, Hofstetter A, Jespers W, Kalinina OV, Kautsar SA, Kim H, Leao TF, Masschelein J, Rees ER, Reher R, Reker D, Schwaller P, Segler M, Skinnider MA, Walker AS, Willighagen EL, Zdrazil B, Ziemert N, Goss RJM, Guyomard P, Volkamer A, Gerwick WH, Kim HU, Müller R, van Wezel GP, van Westen GJP, Hirsch AKH, Linington RG, Robinson SL, Medema MH. Mullowney MW, et al. Among authors: walker as. Nat Rev Drug Discov. 2023 Nov;22(11):895-916. doi: 10.1038/s41573-023-00774-7. Epub 2023 Sep 11. Nat Rev Drug Discov. 2023. PMID: 37697042 Review.
Parsing Molecules for Drug Discovery.
Walker AS, Pishchany G, Clardy J. Walker AS, et al. Biochemistry. 2020 May 5;59(17):1645-1646. doi: 10.1021/acs.biochem.0c00278. Epub 2020 Apr 21. Biochemistry. 2020. PMID: 32315170 Free PMC article. No abstract available.
Nanopore sequencing of influenza A and B in Oxfordshire and the United Kingdom, 2022-23.
Cane J, Sanderson N, Barnett S, Vaughan A, Pott M, Kapel N, Morgan M, Jesuthasan G, Samuel R, Ehsaan M, Boothe H, Haduli E, Studley R, Rourke E, Diamond I, Fowler T, Watson C, Stoesser N, Walker AS, Street T, Eyre DW. Cane J, et al. Among authors: walker as. J Infect. 2024 Apr 29;88(6):106164. doi: 10.1016/j.jinf.2024.106164. Online ahead of print. J Infect. 2024. PMID: 38692359 Free article.
587 results