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Identification of a c-MYB-directed therapeutic for acute myeloid leukemia.
Leukemia. 2022 Jun;36(6):1541-1549. doi: 10.1038/s41375-022-01554-9. Epub 2022 Apr 2.
Leukemia. 2022.
PMID: 35368048
Free PMC article.
In focus: MLL-rearranged leukemia.
de Boer J, Walf-Vorderwülbecke V, Williams O.
de Boer J, et al. Among authors: walf vorderwulbecke v.
Leukemia. 2013 Jun;27(6):1224-8. doi: 10.1038/leu.2013.78. Epub 2013 Mar 21.
Leukemia. 2013.
PMID: 23515098
Review.
Item in Clipboard
Targeting acute myeloid leukemia by drug-induced c-MYB degradation.
Walf-Vorderwülbecke V, Pearce K, Brooks T, Hubank M, van den Heuvel-Eibrink MM, Zwaan CM, Adams S, Edwards D, Bartram J, Samarasinghe S, Ancliff P, Khwaja A, Goulden N, Williams G, de Boer J, Williams O.
Walf-Vorderwülbecke V, et al.
Leukemia. 2018 Apr;32(4):882-889. doi: 10.1038/leu.2017.317. Epub 2017 Nov 1.
Leukemia. 2018.
PMID: 29089643
Item in Clipboard
The AAA+ ATPase RUVBL2 is a critical mediator of MLL-AF9 oncogenesis.
Osaki H, Walf-Vorderwülbecke V, Mangolini M, Zhao L, Horton SJ, Morrone G, Schuringa JJ, de Boer J, Williams O.
Osaki H, et al. Among authors: walf vorderwulbecke v.
Leukemia. 2013 Jul;27(7):1461-8. doi: 10.1038/leu.2013.42. Epub 2013 Feb 13.
Leukemia. 2013.
PMID: 23403462
Item in Clipboard
Acute myeloid leukemia induced by MLL-ENL is cured by oncogene ablation despite acquisition of complex genetic abnormalities.
Horton SJ, Walf-Vorderwülbecke V, Chatters SJ, Sebire NJ, de Boer J, Williams O.
Horton SJ, et al. Among authors: walf vorderwulbecke v.
Blood. 2009 May 14;113(20):4922-9. doi: 10.1182/blood-2008-07-170480. Epub 2008 Nov 24.
Blood. 2009.
PMID: 19029444
Free article.
Item in Clipboard
Frat2 mediates the oncogenic activation of Rac by MLL fusions.
Walf-Vorderwülbecke V, de Boer J, Horton SJ, van Amerongen R, Proost N, Berns A, Williams O.
Walf-Vorderwülbecke V, et al.
Blood. 2012 Dec 6;120(24):4819-28. doi: 10.1182/blood-2012-05-432534. Epub 2012 Oct 16.
Blood. 2012.
PMID: 23074275
Free article.
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STAT3 mediates oncogenic addiction to TEL-AML1 in t(12;21) acute lymphoblastic leukemia.
Mangolini M, de Boer J, Walf-Vorderwülbecke V, Pieters R, den Boer ML, Williams O.
Mangolini M, et al. Among authors: walf vorderwulbecke v.
Blood. 2013 Jul 25;122(4):542-9. doi: 10.1182/blood-2012-11-465252. Epub 2013 Jun 5.
Blood. 2013.
PMID: 23741012
Free article.
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