Waldrop GL - Search Results

1

Optimization and Mechanistic Characterization of Pyridopyrimidine Inhibitors of Bacterial Biotin Carboxylase.

Andrews LD, Kane TR, Dozzo P, Haglund CM, Hilderbrandt DJ, Linsell MS, Machajewski T, McEnroe G, Serio AW, Wlasichuk KB, Neau DB, Pakhomova S, Waldrop GL, Sharp M, Pogliano J, Cirz RT, Cohen F. Andrews LD, et al. Among authors: waldrop gl. J Med Chem. 2019 Aug 22;62(16):7489-7505. doi: 10.1021/acs.jmedchem.9b00625. Epub 2019 Aug 9. J Med Chem. 2019. PMID: 31306011 Free PMC article.

2

The three-dimensional structure of the biotin carboxylase-biotin carboxyl carrier protein complex of E. coli acetyl-CoA carboxylase.

Broussard TC, Kobe MJ, Pakhomova S, Neau DB, Price AE, Champion TS, Waldrop GL. Broussard TC, et al. Among authors: waldrop gl. Structure. 2013 Apr 2;21(4):650-7. doi: 10.1016/j.str.2013.02.001. Epub 2013 Mar 14. Structure. 2013. PMID: 23499019 Free PMC article.

3

Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase.

Broussard TC, Pakhomova S, Neau DB, Bonnot R, Waldrop GL. Broussard TC, et al. Among authors: waldrop gl. Biochemistry. 2015 Jun 23;54(24):3860-70. doi: 10.1021/acs.biochem.5b00340. Epub 2015 Jun 9. Biochemistry. 2015. PMID: 26020841 Free PMC article.

4

Mechanism of biotin carboxylase inhibition by ethyl 4-[[2-chloro-5-(phenylcarbamoyl)phenyl]sulphonylamino]benzoate.

Craft MK, Waldrop GL. Craft MK, et al. Among authors: waldrop gl. J Enzyme Inhib Med Chem. 2022 Dec;37(1):100-108. doi: 10.1080/14756366.2021.1994558. J Enzyme Inhib Med Chem. 2022. PMID: 34894987 Free PMC article.

5

Design, synthesis, and antibacterial properties of dual-ligand inhibitors of acetyl-CoA carboxylase.

Silvers MA, Robertson GT, Taylor CM, Waldrop GL. Silvers MA, et al. Among authors: waldrop gl. J Med Chem. 2014 Nov 13;57(21):8947-59. doi: 10.1021/jm501082n. Epub 2014 Oct 15. J Med Chem. 2014. PMID: 25280369

6

Crystal Structure of Carboxyltransferase from Staphylococcus aureus Bound to the Antibacterial Agent Moiramide B.

Silvers MA, Pakhomova S, Neau DB, Silvers WC, Anzalone N, Taylor CM, Waldrop GL. Silvers MA, et al. Among authors: waldrop gl. Biochemistry. 2016 Aug 23;55(33):4666-74. doi: 10.1021/acs.biochem.6b00641. Epub 2016 Aug 10. Biochemistry. 2016. PMID: 27471863 Free PMC article.

7

Umbrella sampling simulations of biotin carboxylase: is a structure with an open ATP grasp domain stable in solution?

Novak BR, Moldovan D, Waldrop GL, de Queiroz MS. Novak BR, et al. Among authors: waldrop gl. J Phys Chem B. 2009 Jul 30;113(30):10097-103. doi: 10.1021/jp810650q. J Phys Chem B. 2009. PMID: 19585972

8

Kinetic characterization of mutations found in propionic acidemia and methylcrotonylglycinuria: evidence for cooperativity in biotin carboxylase.

Sloane V, Waldrop GL. Sloane V, et al. Among authors: waldrop gl. J Biol Chem. 2004 Apr 16;279(16):15772-8. doi: 10.1074/jbc.M311982200. Epub 2004 Feb 11. J Biol Chem. 2004. PMID: 14960587 Free article.

9

Computational redesign of bacterial biotin carboxylase inhibitors using structure-based virtual screening of combinatorial libraries.

Brylinski M, Waldrop GL. Brylinski M, et al. Among authors: waldrop gl. Molecules. 2014 Apr 2;19(4):4021-45. doi: 10.3390/molecules19044021. Molecules. 2014. PMID: 24699146 Free PMC article.

10

Constituents of cinnamon inhibit bacterial acetyl CoA carboxylase.

Meades G Jr, Henken RL, Waldrop GL, Rahman MM, Gilman SD, Kamatou GP, Viljoen AM, Gibbons S. Meades G Jr, et al. Among authors: waldrop gl. Planta Med. 2010 Oct;76(14):1570-5. doi: 10.1055/s-0030-1249778. Epub 2010 Apr 8. Planta Med. 2010. PMID: 20379951

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