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IFN-γ drives inflammatory bowel disease pathogenesis through VE-cadherin-directed vascular barrier disruption.
Langer V, Vivi E, Regensburger D, Winkler TH, Waldner MJ, Rath T, Schmid B, Skottke L, Lee S, Jeon NL, Wohlfahrt T, Kramer V, Tripal P, Schumann M, Kersting S, Handtrack C, Geppert CI, Suchowski K, Adams RH, Becker C, Ramming A, Naschberger E, Britzen-Laurent N, Stürzl M. Langer V, et al. Among authors: waldner mj. J Clin Invest. 2019 Nov 1;129(11):4691-4707. doi: 10.1172/JCI124884. J Clin Invest. 2019. PMID: 31566580 Free PMC article. Clinical Trial.
Smad7 expression in T cells prevents colitis-associated cancer.
Rizzo A, Waldner MJ, Stolfi C, Sarra M, Fina D, Becker C, Neurath MF, Macdonald TT, Pallone F, Monteleone G, Fantini MC. Rizzo A, et al. Among authors: waldner mj. Cancer Res. 2011 Dec 15;71(24):7423-32. doi: 10.1158/0008-5472.CAN-11-1895. Epub 2011 Oct 25. Cancer Res. 2011. PMID: 22028324
GBP-1 acts as a tumor suppressor in colorectal cancer cells.
Britzen-Laurent N, Lipnik K, Ocker M, Naschberger E, Schellerer VS, Croner RS, Vieth M, Waldner M, Steinberg P, Hohenadl C, Stürzl M. Britzen-Laurent N, et al. Carcinogenesis. 2013 Jan;34(1):153-62. doi: 10.1093/carcin/bgs310. Epub 2012 Oct 6. Carcinogenesis. 2013. PMID: 23042300
Tumor fibroblast-derived epiregulin promotes growth of colitis-associated neoplasms through ERK.
Neufert C, Becker C, Türeci Ö, Waldner MJ, Backert I, Floh K, Atreya I, Leppkes M, Jefremow A, Vieth M, Schneider-Stock R, Klinger P, Greten FR, Threadgill DW, Sahin U, Neurath MF. Neufert C, et al. Among authors: waldner mj. J Clin Invest. 2013 Apr;123(4):1428-43. doi: 10.1172/JCI63748. Epub 2013 Mar 15. J Clin Invest. 2013. PMID: 23549083 Free PMC article.
130 results