Waldmann H - Search Results

1

Identification of pyrazolopyridazinones as PDEδ inhibitors.

Papke B, Murarka S, Vogel HA, Martín-Gago P, Kovacevic M, Truxius DC, Fansa EK, Ismail S, Zimmermann G, Heinelt K, Schultz-Fademrecht C, Al Saabi A, Baumann M, Nussbaumer P, Wittinghofer A, Waldmann H, Bastiaens PI. Papke B, et al. Among authors: waldmann h. Nat Commun. 2016 Apr 20;7:11360. doi: 10.1038/ncomms11360. Nat Commun. 2016. PMID: 27094677 Free PMC article.

2

Bioorganic synthesis of lipid-modified proteins for the study of signal transduction.

Bader B, Kuhn K, Owen DJ, Waldmann H, Wittinghofer A, Kuhlmann J. Bader B, et al. Among authors: waldmann h. Nature. 2000 Jan 13;403(6766):223-6. doi: 10.1038/35003249. Nature. 2000. PMID: 10646611

3

Synthesis of functional Ras lipoproteins and fluorescent derivatives.

Kuhn K, Owen DJ, Bader B, Wittinghofer A, Kuhlmann J, Waldmann H. Kuhn K, et al. Among authors: waldmann h. J Am Chem Soc. 2001 Feb 14;123(6):1023-35. doi: 10.1021/ja002723o. J Am Chem Soc. 2001. PMID: 11456655

4

Synthesis of GTP-derived Ras ligands.

Soulère L, Aldrich C, Daumke O, Gail R, Kissau L, Wittinghofer A, Waldmann H. Soulère L, et al. Among authors: waldmann h. Chembiochem. 2004 Oct 4;5(10):1448-53. doi: 10.1002/cbic.200400133. Chembiochem. 2004. PMID: 15457534

5

Identification of hPin1 inhibitors that induce apoptosis in a mammalian Ras transformed cell line.

Bayer E, Thutewohl M, Christner C, Tradler T, Osterkamp F, Waldmann H, Bayer P. Bayer E, et al. Among authors: waldmann h. Chem Commun (Camb). 2005 Jan 28;(4):516-8. doi: 10.1039/b414037k. Epub 2004 Dec 6. Chem Commun (Camb). 2005. PMID: 15654388

6

An acylation cycle regulates localization and activity of palmitoylated Ras isoforms.

Rocks O, Peyker A, Kahms M, Verveer PJ, Koerner C, Lumbierres M, Kuhlmann J, Waldmann H, Wittinghofer A, Bastiaens PI. Rocks O, et al. Among authors: waldmann h. Science. 2005 Mar 18;307(5716):1746-52. doi: 10.1126/science.1105654. Epub 2005 Feb 10. Science. 2005. PMID: 15705808

7

Intein-mediated in vitro synthesis of lipidated Ras proteins.

Gottlieb D, Grunwald C, Nowak C, Kuhlmann J, Waldmann H. Gottlieb D, et al. Among authors: waldmann h. Chem Commun (Camb). 2006 Jan 21;(3):260-2. doi: 10.1039/b511736d. Epub 2005 Nov 28. Chem Commun (Camb). 2006. PMID: 16391727

8

Lipidated ras and rab peptides and proteins--synthesis, structure, and function.

Brunsveld L, Kuhlmann J, Alexandrov K, Wittinghofer A, Goody RS, Waldmann H. Brunsveld L, et al. Among authors: waldmann h. Angew Chem Int Ed Engl. 2006 Oct 13;45(40):6622-46. doi: 10.1002/anie.200600855. Angew Chem Int Ed Engl. 2006. PMID: 17031879 Review.

9

The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins.

Rocks O, Gerauer M, Vartak N, Koch S, Huang ZP, Pechlivanis M, Kuhlmann J, Brunsveld L, Chandra A, Ellinger B, Waldmann H, Bastiaens PI. Rocks O, et al. Among authors: waldmann h. Cell. 2010 Apr 30;141(3):458-71. doi: 10.1016/j.cell.2010.04.007. Epub 2010 Apr 22. Cell. 2010. PMID: 20416930 Free article.

10

Small-molecule inhibition of APT1 affects Ras localization and signaling.

Dekker FJ, Rocks O, Vartak N, Menninger S, Hedberg C, Balamurugan R, Wetzel S, Renner S, Gerauer M, Schölermann B, Rusch M, Kramer JW, Rauh D, Coates GW, Brunsveld L, Bastiaens PI, Waldmann H. Dekker FJ, et al. Among authors: waldmann h. Nat Chem Biol. 2010 Jun;6(6):449-56. doi: 10.1038/nchembio.362. Epub 2010 Apr 25. Nat Chem Biol. 2010. PMID: 20418879

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