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803 results

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Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and Pharmacokinetics.
Kus K, Walczak M, Maslak E, Zakrzewska A, Gonciarz-Dytman A, Zabielski P, Sitek B, Wandzel K, Kij A, Chabowski A, Holland RJ, Saavedra JE, Keefer LK, Chlopicki S. Kus K, et al. Among authors: walczak m. Drug Metab Dispos. 2015 Jul;43(7):1028-36. doi: 10.1124/dmd.115.063388. Epub 2015 Apr 13. Drug Metab Dispos. 2015. PMID: 25870102 Free PMC article.
The liver-selective NO donor, V-PYRRO/NO, protects against liver steatosis and improves postprandial glucose tolerance in mice fed high fat diet.
Maslak E, Zabielski P, Kochan K, Kus K, Jasztal A, Sitek B, Proniewski B, Wojcik T, Gula K, Kij A, Walczak M, Baranska M, Chabowski A, Holland RJ, Saavedra JE, Keefer LK, Chlopicki S. Maslak E, et al. Among authors: walczak m. Biochem Pharmacol. 2015 Feb 1;93(3):389-400. doi: 10.1016/j.bcp.2014.12.004. Epub 2014 Dec 19. Biochem Pharmacol. 2015. PMID: 25534988
Differential involvement of IL-6 in the early and late phase of 1-methylnicotinamide (MNA) release in Concanavalin A-induced hepatitis.
Sternak M, Jakubowski A, Czarnowska E, Slominska EM, Smolenski RT, Szafarz M, Walczak M, Sitek B, Wojcik T, Jasztal A, Kaminski K, Chlopicki S. Sternak M, et al. Among authors: walczak m. Int Immunopharmacol. 2015 Sep;28(1):105-14. doi: 10.1016/j.intimp.2015.04.053. Epub 2015 May 11. Int Immunopharmacol. 2015. PMID: 25976094
The antidepressant-like activity of 6-methoxy-2-[4-(2-methoxyphenyl)piperazin-1-yl]-9H-xanthen-9-one involves serotonergic 5-HT(1A) and 5-HT(2A/C) receptors activation.
Pytka K, Walczak M, Kij A, Rapacz A, Siwek A, Kazek G, Olczyk A, Gałuszka A, Waszkielewicz A, Marona H, Sapa J, Filipek B. Pytka K, et al. Among authors: walczak m. Eur J Pharmacol. 2015 Oct 5;764:537-546. doi: 10.1016/j.ejphar.2015.07.041. Epub 2015 Jul 22. Eur J Pharmacol. 2015. PMID: 26210317
Antiatherosclerotic Effects of 1-Methylnicotinamide in Apolipoprotein E/Low-Density Lipoprotein Receptor-Deficient Mice: A Comparison with Nicotinic Acid.
Mateuszuk L, Jasztal A, Maslak E, Gasior-Glogowska M, Baranska M, Sitek B, Kostogrys R, Zakrzewska A, Kij A, Walczak M, Chlopicki S. Mateuszuk L, et al. Among authors: walczak m. J Pharmacol Exp Ther. 2016 Feb;356(2):514-24. doi: 10.1124/jpet.115.228643. Epub 2015 Dec 2. J Pharmacol Exp Ther. 2016. PMID: 26631491 Free PMC article.
803 results