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Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repair.
Martinez Lagunas K, Savcigil DP, Zrilic M, Carvajal Fraile C, Craxton A, Self E, Uranga-Murillo I, de Miguel D, Arias M, Willenborg S, Piekarek M, Albert MC, Nugraha K, Lisewski I, Janakova E, Igual N, Tonnus W, Hildebrandt X, Ibrahim M, Ballegeer M, Saelens X, Kueh A, Meier P, Linkermann A, Pardo J, Eming S, Walczak H, MacFarlane M, Peltzer N, Annibaldi A. Martinez Lagunas K, et al. Among authors: walczak h. Sci Adv. 2023 Jul 28;9(30):eadg2829. doi: 10.1126/sciadv.adg2829. Epub 2023 Jul 26. Sci Adv. 2023. PMID: 37494451 Free PMC article.
Necroptosis in immunity and ischemia-reperfusion injury.
Linkermann A, Hackl MJ, Kunzendorf U, Walczak H, Krautwald S, Jevnikar AM. Linkermann A, et al. Among authors: walczak h. Am J Transplant. 2013 Nov;13(11):2797-804. doi: 10.1111/ajt.12448. Epub 2013 Sep 18. Am J Transplant. 2013. PMID: 24103029 Free article. Review.
Ubiquitin in the immune system.
Zinngrebe J, Montinaro A, Peltzer N, Walczak H. Zinngrebe J, et al. Among authors: walczak h. EMBO Rep. 2014 Jan;15(1):28-45. doi: 10.1002/embr.201338025. Epub 2013 Dec 27. EMBO Rep. 2014. PMID: 24375678 Free PMC article. Review.
HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death.
Peltzer N, Rieser E, Taraborrelli L, Draber P, Darding M, Pernaute B, Shimizu Y, Sarr A, Draberova H, Montinaro A, Martinez-Barbera JP, Silke J, Rodriguez TA, Walczak H. Peltzer N, et al. Among authors: walczak h. Cell Rep. 2014 Oct 9;9(1):153-165. doi: 10.1016/j.celrep.2014.08.066. Epub 2014 Oct 2. Cell Rep. 2014. PMID: 25284787 Free article.
TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice.
Rickard JA, Anderton H, Etemadi N, Nachbur U, Darding M, Peltzer N, Lalaoui N, Lawlor KE, Vanyai H, Hall C, Bankovacki A, Gangoda L, Wong WW, Corbin J, Huang C, Mocarski ES, Murphy JM, Alexander WS, Voss AK, Vaux DL, Kaiser WJ, Walczak H, Silke J. Rickard JA, et al. Among authors: walczak h. Elife. 2014 Dec 2;3:e03464. doi: 10.7554/eLife.03464. Elife. 2014. PMID: 25443632 Free PMC article.
LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes.
Draber P, Kupka S, Reichert M, Draberova H, Lafont E, de Miguel D, Spilgies L, Surinova S, Taraborrelli L, Hartwig T, Rieser E, Martino L, Rittinger K, Walczak H. Draber P, et al. Among authors: walczak h. Cell Rep. 2015 Dec 15;13(10):2258-72. doi: 10.1016/j.celrep.2015.11.009. Epub 2015 Dec 6. Cell Rep. 2015. PMID: 26670046 Free PMC article.
Holding RIPK1 on the Ubiquitin Leash in TNFR1 Signaling.
Peltzer N, Darding M, Walczak H. Peltzer N, et al. Among authors: walczak h. Trends Cell Biol. 2016 Jun;26(6):445-461. doi: 10.1016/j.tcb.2016.01.006. Epub 2016 Feb 11. Trends Cell Biol. 2016. PMID: 26877205 Review.
Onto better TRAILs for cancer treatment.
de Miguel D, Lemke J, Anel A, Walczak H, Martinez-Lostao L. de Miguel D, et al. Among authors: walczak h. Cell Death Differ. 2016 May;23(5):733-47. doi: 10.1038/cdd.2015.174. Epub 2016 Mar 4. Cell Death Differ. 2016. PMID: 26943322 Free PMC article. Review.
223 results